Integrin Targeted Gold Nanoparticles Potentiate Cancer Radiation Sensitivity: Synthesizing and modifying gold nanorods to target cancer cells

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Abstract

Recent rapid advancements in nanotechnology have enabled precision medicine to be realized through the modification of functional nanoparticles to carry therapeutic cargos while concentrated in lesion sites via surface conjugation of targeting moieties. Moreover, the endogenous properties of the particles to produce contrast of current or novel imaging modalities allow the integration of diagnostic imaging and therapeutics in one regimen to benefit clinical disease management [1], [2]. Gold nanoparticles (GNPs) have long been investigated for their potential biomedical applications because of their biocompatibility and well-characterized surface chemistry for various functional modifications.

Original languageEnglish
Article number7387738
Pages (from-to)4-15
Number of pages12
JournalIEEE Nanotechnology Magazine
Volume10
Issue number1
DOIs
Publication statusPublished - 2016 Mar 1

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All Science Journal Classification (ASJC) codes

  • Mechanical Engineering
  • Electrical and Electronic Engineering

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