Inverse relationship between central obesity and osteoporosis in osteoporotic drug naive elderly females: The tianliao old people (top) study

Chin-Sung Chang, Yin-Fan Chang, Mei Wen Wang, Chuan-Yu Chen, Yu Jang Chao, Hsuan Jui Chang, Po Hsiu Kuo, Yi-Ching Yang, Chih-Hsing Wu

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

To examine the relationship between central obesity and osteoporosis in elderly females in a rural community, a total of 368 ambulatory elderly women were recruited by random sampling during July 2009. Structured questionnaires were completed to survey possible osteoporosis-related risk factors. Subjects were dichotomized into either noncentral obese (waist circumference [WC] < 80. cm) or central obese subgroups (WC ≥ 80. cm) for further analysis. Bone mineral densities were scanned by dual-energy X-ray absorptiometry installed in a mobile bus. Thoracolumbar spine X-ray examination was interpreted by the same radiologist. Of the 365 subjects with completed data, 275 (75.3%) aged women were classified as having osteoporosis based on diagnostic Model III. Compared with the nonosteoporosis subjects, the subjects with osteoporosis had relatively higher mean age, lower body mass index, and a lower percentage of central obesity. Using the binary logistic regression method, central obesity was negatively associated with osteoporosis in all 3 models (odds ratios in the 3 models were 0.348, 95% confidence interval [CI]: 0.130-0.927; 0.444, 95% CI: 0.218-0.905; and 0.415, 95% CI: 0.184-0.936, respectively; p< 0.05). Our study suggests that the paradox between central obesity and osteoporosis in elderly women should be of concern and warrants further study.

Original languageEnglish
Pages (from-to)204-211
Number of pages8
JournalJournal of Clinical Densitometry
Volume16
Issue number2
DOIs
Publication statusPublished - 2013 Apr 1

Fingerprint

Abdominal Obesity
Osteoporosis
Pharmaceutical Preparations
Waist Circumference
Confidence Intervals
Photon Absorptiometry
Motor Vehicles
Rural Population
Bone Density
Spine
Body Mass Index
Logistic Models
Odds Ratio
X-Rays

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

@article{eba8199f1da94594b0e97c0e47bdec01,
title = "Inverse relationship between central obesity and osteoporosis in osteoporotic drug naive elderly females: The tianliao old people (top) study",
abstract = "To examine the relationship between central obesity and osteoporosis in elderly females in a rural community, a total of 368 ambulatory elderly women were recruited by random sampling during July 2009. Structured questionnaires were completed to survey possible osteoporosis-related risk factors. Subjects were dichotomized into either noncentral obese (waist circumference [WC] < 80. cm) or central obese subgroups (WC ≥ 80. cm) for further analysis. Bone mineral densities were scanned by dual-energy X-ray absorptiometry installed in a mobile bus. Thoracolumbar spine X-ray examination was interpreted by the same radiologist. Of the 365 subjects with completed data, 275 (75.3{\%}) aged women were classified as having osteoporosis based on diagnostic Model III. Compared with the nonosteoporosis subjects, the subjects with osteoporosis had relatively higher mean age, lower body mass index, and a lower percentage of central obesity. Using the binary logistic regression method, central obesity was negatively associated with osteoporosis in all 3 models (odds ratios in the 3 models were 0.348, 95{\%} confidence interval [CI]: 0.130-0.927; 0.444, 95{\%} CI: 0.218-0.905; and 0.415, 95{\%} CI: 0.184-0.936, respectively; p< 0.05). Our study suggests that the paradox between central obesity and osteoporosis in elderly women should be of concern and warrants further study.",
author = "Chin-Sung Chang and Yin-Fan Chang and Wang, {Mei Wen} and Chuan-Yu Chen and Chao, {Yu Jang} and Chang, {Hsuan Jui} and Kuo, {Po Hsiu} and Yi-Ching Yang and Chih-Hsing Wu",
year = "2013",
month = "4",
day = "1",
doi = "10.1016/j.jocd.2012.03.008",
language = "English",
volume = "16",
pages = "204--211",
journal = "Journal of Clinical Densitometry",
issn = "1094-6950",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Inverse relationship between central obesity and osteoporosis in osteoporotic drug naive elderly females

T2 - The tianliao old people (top) study

AU - Chang, Chin-Sung

AU - Chang, Yin-Fan

AU - Wang, Mei Wen

AU - Chen, Chuan-Yu

AU - Chao, Yu Jang

AU - Chang, Hsuan Jui

AU - Kuo, Po Hsiu

AU - Yang, Yi-Ching

AU - Wu, Chih-Hsing

PY - 2013/4/1

Y1 - 2013/4/1

N2 - To examine the relationship between central obesity and osteoporosis in elderly females in a rural community, a total of 368 ambulatory elderly women were recruited by random sampling during July 2009. Structured questionnaires were completed to survey possible osteoporosis-related risk factors. Subjects were dichotomized into either noncentral obese (waist circumference [WC] < 80. cm) or central obese subgroups (WC ≥ 80. cm) for further analysis. Bone mineral densities were scanned by dual-energy X-ray absorptiometry installed in a mobile bus. Thoracolumbar spine X-ray examination was interpreted by the same radiologist. Of the 365 subjects with completed data, 275 (75.3%) aged women were classified as having osteoporosis based on diagnostic Model III. Compared with the nonosteoporosis subjects, the subjects with osteoporosis had relatively higher mean age, lower body mass index, and a lower percentage of central obesity. Using the binary logistic regression method, central obesity was negatively associated with osteoporosis in all 3 models (odds ratios in the 3 models were 0.348, 95% confidence interval [CI]: 0.130-0.927; 0.444, 95% CI: 0.218-0.905; and 0.415, 95% CI: 0.184-0.936, respectively; p< 0.05). Our study suggests that the paradox between central obesity and osteoporosis in elderly women should be of concern and warrants further study.

AB - To examine the relationship between central obesity and osteoporosis in elderly females in a rural community, a total of 368 ambulatory elderly women were recruited by random sampling during July 2009. Structured questionnaires were completed to survey possible osteoporosis-related risk factors. Subjects were dichotomized into either noncentral obese (waist circumference [WC] < 80. cm) or central obese subgroups (WC ≥ 80. cm) for further analysis. Bone mineral densities were scanned by dual-energy X-ray absorptiometry installed in a mobile bus. Thoracolumbar spine X-ray examination was interpreted by the same radiologist. Of the 365 subjects with completed data, 275 (75.3%) aged women were classified as having osteoporosis based on diagnostic Model III. Compared with the nonosteoporosis subjects, the subjects with osteoporosis had relatively higher mean age, lower body mass index, and a lower percentage of central obesity. Using the binary logistic regression method, central obesity was negatively associated with osteoporosis in all 3 models (odds ratios in the 3 models were 0.348, 95% confidence interval [CI]: 0.130-0.927; 0.444, 95% CI: 0.218-0.905; and 0.415, 95% CI: 0.184-0.936, respectively; p< 0.05). Our study suggests that the paradox between central obesity and osteoporosis in elderly women should be of concern and warrants further study.

UR - http://www.scopus.com/inward/record.url?scp=84877031642&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84877031642&partnerID=8YFLogxK

U2 - 10.1016/j.jocd.2012.03.008

DO - 10.1016/j.jocd.2012.03.008

M3 - Article

C2 - 22717906

AN - SCOPUS:84877031642

VL - 16

SP - 204

EP - 211

JO - Journal of Clinical Densitometry

JF - Journal of Clinical Densitometry

SN - 1094-6950

IS - 2

ER -