Abstract

Most studies reporting an inverse association between the consumption of vegetables and fruits and head and neck cancer (HNC) risk were conducted in Western populations and only a few included East Asians. The current case-control study investigated the association between diet and HNC risk using data of 838 HNC cases and 998 controls from a case-control study of HNC conducted in Taiwan. Each participant was asked about their consumption of fresh vegetables, pickled vegetables, fresh fruits, citrus fruits, meat, processed meat, fish, egg, and dairy products. Unconditional logistic regression was performed to estimate the odds ratio (OR) and 95% confidence interval (CI) of HNC risk associated with each food category, adjusted for sex, age, education, and use of alcohol, betel quid and cigarette. An inverse association was observed between HNC risk and daily intake of fresh vegetables (OR = 0.44, 95% CI: 0.20-0.95, p-trend = 0.002) or fruits (OR = 0.55, 95% CI: 0.43-0.72, p-trend = 0.00001). Individuals who did not consume fresh fruits and vegetables daily had more than double the risk of HNC compared to those with daily intake of vegetables and fruits (OR= 2.24, 95% CI: 1.54-3.25). The results of the current study supported an inverse association between the consumption of fresh vegetables and fruits and HNC risk. In addition to cessation of cigarette smoking and betel quid chewing and reduction of alcohol drinking, a public health campaign for preventing the occurrence of HNC should promote a healthy diet that contains plenty of fresh vegetables and fruits.

Original languageEnglish
Pages (from-to)98865-98875
Number of pages11
JournalOncotarget
Volume8
Issue number58
DOIs
Publication statusPublished - 2017 Jan 1

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Head and Neck Neoplasms
Taiwan
Vegetables
Diet
Fruit
Odds Ratio
Confidence Intervals
Meat
Case-Control Studies
Fish Products
Sex Education
Dairy Products
Citrus
Mastication
Health Promotion
Tobacco Products
Alcohol Drinking
Ovum
Public Health
Logistic Models

All Science Journal Classification (ASJC) codes

  • Oncology

Cite this

@article{1a7a5b8c54b1478aa74060f70875852b,
title = "Investigating the association between diet and risk of head and neck cancer in Taiwan",
abstract = "Most studies reporting an inverse association between the consumption of vegetables and fruits and head and neck cancer (HNC) risk were conducted in Western populations and only a few included East Asians. The current case-control study investigated the association between diet and HNC risk using data of 838 HNC cases and 998 controls from a case-control study of HNC conducted in Taiwan. Each participant was asked about their consumption of fresh vegetables, pickled vegetables, fresh fruits, citrus fruits, meat, processed meat, fish, egg, and dairy products. Unconditional logistic regression was performed to estimate the odds ratio (OR) and 95{\%} confidence interval (CI) of HNC risk associated with each food category, adjusted for sex, age, education, and use of alcohol, betel quid and cigarette. An inverse association was observed between HNC risk and daily intake of fresh vegetables (OR = 0.44, 95{\%} CI: 0.20-0.95, p-trend = 0.002) or fruits (OR = 0.55, 95{\%} CI: 0.43-0.72, p-trend = 0.00001). Individuals who did not consume fresh fruits and vegetables daily had more than double the risk of HNC compared to those with daily intake of vegetables and fruits (OR= 2.24, 95{\%} CI: 1.54-3.25). The results of the current study supported an inverse association between the consumption of fresh vegetables and fruits and HNC risk. In addition to cessation of cigarette smoking and betel quid chewing and reduction of alcohol drinking, a public health campaign for preventing the occurrence of HNC should promote a healthy diet that contains plenty of fresh vegetables and fruits.",
author = "Chang, {Chan Chi} and Lee, {Wei Ting} and Lee, {Yao Chou} and Huang, {Cheng Chih} and Ou, {Chun Yen} and Lin, {Yu Hsuan} and Huang, {Jehn Shyun} and Wong, {Tung Yiu} and Chen, {Ken Chung} and Hsiao, {Jenn Ren} and Lu, {Yu Cheng} and Tsai, {Sen Tien} and Lai, {Yu Hsuan} and Wu, {Yuan Hua} and Hsueh, {Wei Ting} and Yen, {Chia Jui} and Wu, {Shang Yin} and Chang, {Jang Yang} and Fang, {Sheen Yie} and Wu, {Jiunn Liang} and Lin, {Chen Lin} and Weng, {Ya Ling} and Yang, {Han Chien} and Chen, {Yu Shan} and Chang, {Jeffrey S.}",
year = "2017",
month = "1",
day = "1",
doi = "10.18632/oncotarget.22010",
language = "English",
volume = "8",
pages = "98865--98875",
journal = "Oncotarget",
issn = "1949-2553",
publisher = "Impact Journals",
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TY - JOUR

T1 - Investigating the association between diet and risk of head and neck cancer in Taiwan

AU - Chang, Chan Chi

AU - Lee, Wei Ting

AU - Lee, Yao Chou

AU - Huang, Cheng Chih

AU - Ou, Chun Yen

AU - Lin, Yu Hsuan

AU - Huang, Jehn Shyun

AU - Wong, Tung Yiu

AU - Chen, Ken Chung

AU - Hsiao, Jenn Ren

AU - Lu, Yu Cheng

AU - Tsai, Sen Tien

AU - Lai, Yu Hsuan

AU - Wu, Yuan Hua

AU - Hsueh, Wei Ting

AU - Yen, Chia Jui

AU - Wu, Shang Yin

AU - Chang, Jang Yang

AU - Fang, Sheen Yie

AU - Wu, Jiunn Liang

AU - Lin, Chen Lin

AU - Weng, Ya Ling

AU - Yang, Han Chien

AU - Chen, Yu Shan

AU - Chang, Jeffrey S.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Most studies reporting an inverse association between the consumption of vegetables and fruits and head and neck cancer (HNC) risk were conducted in Western populations and only a few included East Asians. The current case-control study investigated the association between diet and HNC risk using data of 838 HNC cases and 998 controls from a case-control study of HNC conducted in Taiwan. Each participant was asked about their consumption of fresh vegetables, pickled vegetables, fresh fruits, citrus fruits, meat, processed meat, fish, egg, and dairy products. Unconditional logistic regression was performed to estimate the odds ratio (OR) and 95% confidence interval (CI) of HNC risk associated with each food category, adjusted for sex, age, education, and use of alcohol, betel quid and cigarette. An inverse association was observed between HNC risk and daily intake of fresh vegetables (OR = 0.44, 95% CI: 0.20-0.95, p-trend = 0.002) or fruits (OR = 0.55, 95% CI: 0.43-0.72, p-trend = 0.00001). Individuals who did not consume fresh fruits and vegetables daily had more than double the risk of HNC compared to those with daily intake of vegetables and fruits (OR= 2.24, 95% CI: 1.54-3.25). The results of the current study supported an inverse association between the consumption of fresh vegetables and fruits and HNC risk. In addition to cessation of cigarette smoking and betel quid chewing and reduction of alcohol drinking, a public health campaign for preventing the occurrence of HNC should promote a healthy diet that contains plenty of fresh vegetables and fruits.

AB - Most studies reporting an inverse association between the consumption of vegetables and fruits and head and neck cancer (HNC) risk were conducted in Western populations and only a few included East Asians. The current case-control study investigated the association between diet and HNC risk using data of 838 HNC cases and 998 controls from a case-control study of HNC conducted in Taiwan. Each participant was asked about their consumption of fresh vegetables, pickled vegetables, fresh fruits, citrus fruits, meat, processed meat, fish, egg, and dairy products. Unconditional logistic regression was performed to estimate the odds ratio (OR) and 95% confidence interval (CI) of HNC risk associated with each food category, adjusted for sex, age, education, and use of alcohol, betel quid and cigarette. An inverse association was observed between HNC risk and daily intake of fresh vegetables (OR = 0.44, 95% CI: 0.20-0.95, p-trend = 0.002) or fruits (OR = 0.55, 95% CI: 0.43-0.72, p-trend = 0.00001). Individuals who did not consume fresh fruits and vegetables daily had more than double the risk of HNC compared to those with daily intake of vegetables and fruits (OR= 2.24, 95% CI: 1.54-3.25). The results of the current study supported an inverse association between the consumption of fresh vegetables and fruits and HNC risk. In addition to cessation of cigarette smoking and betel quid chewing and reduction of alcohol drinking, a public health campaign for preventing the occurrence of HNC should promote a healthy diet that contains plenty of fresh vegetables and fruits.

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