Ionone derivatives from the mycelium of Phellinus linteus and the inhibitory effect on activated rat hepatic stellate cells

Shiow Chyn Huang, Ping Chung Kuo, Hsin Yi Hung, Tai Long Pan, Fu An Chen, Tian Shung Wu

Research output: Contribution to journalLetter

3 Citations (Scopus)

Abstract

Three new γ-ionylideneacetic acid derivatives, phellinulins A–C (1–3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.

Original languageEnglish
Article number681
JournalInternational journal of molecular sciences
Volume17
Issue number5
DOIs
Publication statusPublished - 2016 May 6

Fingerprint

Norisoprenoids
Hepatic Stellate Cells
fibrosis
Spectroscopic analysis
Mycelium
spectroscopic analysis
rats
Rats
alternating current
Fibrosis
examination
Derivatives
acids
Acids
Liver
cells
Phellinus linteus extract

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Cite this

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abstract = "Three new γ-ionylideneacetic acid derivatives, phellinulins A–C (1–3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.",
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Ionone derivatives from the mycelium of Phellinus linteus and the inhibitory effect on activated rat hepatic stellate cells. / Huang, Shiow Chyn; Kuo, Ping Chung; Hung, Hsin Yi; Pan, Tai Long; Chen, Fu An; Wu, Tian Shung.

In: International journal of molecular sciences, Vol. 17, No. 5, 681, 06.05.2016.

Research output: Contribution to journalLetter

TY - JOUR

T1 - Ionone derivatives from the mycelium of Phellinus linteus and the inhibitory effect on activated rat hepatic stellate cells

AU - Huang, Shiow Chyn

AU - Kuo, Ping Chung

AU - Hung, Hsin Yi

AU - Pan, Tai Long

AU - Chen, Fu An

AU - Wu, Tian Shung

PY - 2016/5/6

Y1 - 2016/5/6

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