Ionone derivatives from the mycelium of Phellinus linteus and the inhibitory effect on activated rat hepatic stellate cells

Shiow Chyn Huang, Ping-Chung Kuo, Hsin-Yi Hung, Tai Long Pan, Fu An Chen, Tian-Shung Wu

Research output: Contribution to journalLetter

2 Citations (Scopus)

Abstract

Three new γ-ionylideneacetic acid derivatives, phellinulins A–C (1–3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.

Original languageEnglish
Article number681
JournalInternational journal of molecular sciences
Volume17
Issue number5
DOIs
Publication statusPublished - 2016 May 6

Fingerprint

Norisoprenoids
Hepatic Stellate Cells
fibrosis
Spectroscopic analysis
Mycelium
spectroscopic analysis
rats
Rats
alternating current
Fibrosis
examination
Derivatives
acids
Acids
Liver
cells
Phellinus linteus extract

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Cite this

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abstract = "Three new γ-ionylideneacetic acid derivatives, phellinulins A–C (1–3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.",
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Ionone derivatives from the mycelium of Phellinus linteus and the inhibitory effect on activated rat hepatic stellate cells. / Huang, Shiow Chyn; Kuo, Ping-Chung; Hung, Hsin-Yi; Pan, Tai Long; Chen, Fu An; Wu, Tian-Shung.

In: International journal of molecular sciences, Vol. 17, No. 5, 681, 06.05.2016.

Research output: Contribution to journalLetter

TY - JOUR

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AU - Huang, Shiow Chyn

AU - Kuo, Ping-Chung

AU - Hung, Hsin-Yi

AU - Pan, Tai Long

AU - Chen, Fu An

AU - Wu, Tian-Shung

PY - 2016/5/6

Y1 - 2016/5/6

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