Ionone derivatives from the mycelium of Phellinus linteus and the inhibitory effect on activated rat hepatic stellate cells

Shiow Chyn Huang, Ping Chung Kuo, Hsin Yi Hung, Tai Long Pan, Fu An Chen, Tian Shung Wu

Research output: Contribution to journalLetterpeer-review

9 Citations (Scopus)

Abstract

Three new γ-ionylideneacetic acid derivatives, phellinulins A–C (1–3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.

Original languageEnglish
Article number681
JournalInternational journal of molecular sciences
Volume17
Issue number5
DOIs
Publication statusPublished - 2016 May 6

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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