Isolation and cytotoxicity of rhinacanthin-A and -B, two; naphthoquinones, from Rhinacanthus nasutus

Tian Shung Wu, Hsien Ju Tien, Mou Yung Yeh, Kuo Hsiung Lee

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Rhinacanthin-A and -B, two new naphthoquinones, and the known lupeol, β-sitosterol, stigmasterol, as well as the glucosides of β-sitosterol and stigmasterol were isolated from the roots of Rhinacanthus nasutus. The structures of rhinacanthin-A and -B were elucidated on the basis of spectral analyses. Rhinacanthin-B demonstrated significant Cytotoxicity (ED50 = 3.0μg/ ml) in the KB tissue culture cell.

Original languageEnglish
Pages (from-to)3787-3788
Number of pages2
Issue number12
Publication statusPublished - 1988


All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

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