6,7-Demethylenedesoxypodophyllotoxin (1) was isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) collected in Taiwan, together with several known lignans. This is the first example of the occurrence of 1 in a natural source. The assignments of the 13C-nuclear magnetic resonance signals of several podophyllotoxin analogues isolated from this plant were also established by means of two-dimensional H-C correlation spectroscopy (COSY) and H-C long range COSY techniques.
All Science Journal Classification (ASJC) codes
- Drug Discovery