Isolation of 6,7-demethylenedesoxypodophyllotoxin from Hernandia ovigera

C. Ito, T. Matsui, T. S. Wu, H. Furukawa

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

6,7-Demethylenedesoxypodophyllotoxin (1) was isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) collected in Taiwan, together with several known lignans. This is the first example of the occurrence of 1 in a natural source. The assignments of the 13C-nuclear magnetic resonance signals of several podophyllotoxin analogues isolated from this plant were also established by means of two-dimensional H-C correlation spectroscopy (COSY) and H-C long range COSY techniques.

Original languageEnglish
Pages (from-to)1318-1321
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume40
Issue number5
DOIs
Publication statusPublished - 1992

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

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