Isolation of 6,7-demethylenedesoxypodophyllotoxin from Hernandia ovigera

C. Ito; T. Matsui; T. S. Wu; H. Furukawa

doi:10.1248/cpb.40.1318

Isolation of 6,7-demethylenedesoxypodophyllotoxin from Hernandia ovigera

C. Ito
, T. Matsui
, T. S. Wu
, H. Furukawa

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

6,7-Demethylenedesoxypodophyllotoxin (1) was isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) collected in Taiwan, together with several known lignans. This is the first example of the occurrence of 1 in a natural source. The assignments of the ¹³C-nuclear magnetic resonance signals of several podophyllotoxin analogues isolated from this plant were also established by means of two-dimensional H-C correlation spectroscopy (COSY) and H-C long range COSY techniques.

Original language	English
Pages (from-to)	1318-1321
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	40
Issue number	5
DOIs	https://doi.org/10.1248/cpb.40.1318
Publication status	Published - 1992

All Science Journal Classification (ASJC) codes

General Chemistry
Drug Discovery

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abstract = "6,7-Demethylenedesoxypodophyllotoxin (1) was isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) collected in Taiwan, together with several known lignans. This is the first example of the occurrence of 1 in a natural source. The assignments of the 13C-nuclear magnetic resonance signals of several podophyllotoxin analogues isolated from this plant were also established by means of two-dimensional H-C correlation spectroscopy (COSY) and H-C long range COSY techniques.",

author = "C. Ito and T. Matsui and Wu, \{T. S.\} and H. Furukawa",

year = "1992",

doi = "10.1248/cpb.40.1318",

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journal = "Chemical and Pharmaceutical Bulletin",

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AU - Ito, C.

AU - Matsui, T.

AU - Wu, T. S.

AU - Furukawa, H.

PY - 1992

Y1 - 1992

N2 - 6,7-Demethylenedesoxypodophyllotoxin (1) was isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) collected in Taiwan, together with several known lignans. This is the first example of the occurrence of 1 in a natural source. The assignments of the 13C-nuclear magnetic resonance signals of several podophyllotoxin analogues isolated from this plant were also established by means of two-dimensional H-C correlation spectroscopy (COSY) and H-C long range COSY techniques.

AB - 6,7-Demethylenedesoxypodophyllotoxin (1) was isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) collected in Taiwan, together with several known lignans. This is the first example of the occurrence of 1 in a natural source. The assignments of the 13C-nuclear magnetic resonance signals of several podophyllotoxin analogues isolated from this plant were also established by means of two-dimensional H-C correlation spectroscopy (COSY) and H-C long range COSY techniques.

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UR - https://www.scopus.com/pages/publications/0026634779#tab=citedBy

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DO - 10.1248/cpb.40.1318

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SN - 0009-2363

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JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 5

ER -

Isolation of 6,7-demethylenedesoxypodophyllotoxin from Hernandia ovigera

Abstract

All Science Journal Classification (ASJC) codes

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