Abstract
Chemical investigation of the bark of Calocedrus macrolepis var. formosana, an endemic tree in Taiwan, has led to the isolation of a novel terpenoid 1. Compound 1 with a rare C35 skeleton constructed by a diterpene and a sesquiterpene moieties. Its structure was elucidated by spectroscopic interpretations. The anti-proliferation activity of 1 against human oral epidermoid carcinoma KB cells was evaluated, and the IC50 value was determined to be 9.2 ± 0.4 μM.
Original language | English |
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Pages (from-to) | 515-517 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 52 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2011 Jan 26 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry