Laparoscopic surgery for large left lateral liver tumors: safety and oncologic outcomes

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Although laparoscopic hepatectomy has been proven to be safe and reliable, the influence of tumor size on the feasibility of laparoscopic left lateral segmentectomy (LLLS) is unclear. We retrospectively reviewed our surgical results focusing on hepatic tumor located in the left lateral segment. Methods: From January 2003 to June 2016, patients who underwent left lateral segmentectomy were retrospectively reviewed, and data were collected on patient characteristics, peri-operative outcomes, and pathologic results. Patients with intrahepatic stone, cystic lesion, or unmeasurable tumor size were excluded. The continuous variables were compared using the Mann–Whitney U test and categorical variables using the Chi square or Fisher’s exact test. The overall and disease-free survival rates were computed using the Kaplan–Meier method and compared using the log-rank test. Results: A total of 103 patients were enrolled for analysis. Among the patients with tumors larger than 5 cm in the left lateral segment, those who underwent laparoscopic surgery had significantly shorter hospital stay and larger resection margin than those who underwent open surgery. The surgical results of the patients who underwent LLLS were not significantly different from those of the patients with tumors larger than 5 cm. Specifically, the 5-year overall survival and disease-free survival rates of the patients with hepatocellular carcinoma (HCC) larger than 5 cm who underwent LLLS were comparable to those of the patients who underwent open left lateral segmentectomy. Conclusions: LLLS is safe and also feasible for hepatic tumors larger than 5 cm. For HCCs larger than 5 cm, the laparoscopic approach yields satisfying oncologic outcomes as the open approach.

Original languageEnglish
Pages (from-to)4314-4320
Number of pages7
JournalSurgical Endoscopy
Volume32
Issue number10
DOIs
Publication statusPublished - 2018 Oct 1

Fingerprint

Laparoscopy
Segmental Mastectomy
Safety
Liver
Neoplasms
Disease-Free Survival
Survival Rate
Hepatectomy
Hepatocellular Carcinoma
Length of Stay
Survival

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

@article{708d54cf7bec4d4eb594d0dc673f842b,
title = "Laparoscopic surgery for large left lateral liver tumors: safety and oncologic outcomes",
abstract = "Background: Although laparoscopic hepatectomy has been proven to be safe and reliable, the influence of tumor size on the feasibility of laparoscopic left lateral segmentectomy (LLLS) is unclear. We retrospectively reviewed our surgical results focusing on hepatic tumor located in the left lateral segment. Methods: From January 2003 to June 2016, patients who underwent left lateral segmentectomy were retrospectively reviewed, and data were collected on patient characteristics, peri-operative outcomes, and pathologic results. Patients with intrahepatic stone, cystic lesion, or unmeasurable tumor size were excluded. The continuous variables were compared using the Mann–Whitney U test and categorical variables using the Chi square or Fisher’s exact test. The overall and disease-free survival rates were computed using the Kaplan–Meier method and compared using the log-rank test. Results: A total of 103 patients were enrolled for analysis. Among the patients with tumors larger than 5 cm in the left lateral segment, those who underwent laparoscopic surgery had significantly shorter hospital stay and larger resection margin than those who underwent open surgery. The surgical results of the patients who underwent LLLS were not significantly different from those of the patients with tumors larger than 5 cm. Specifically, the 5-year overall survival and disease-free survival rates of the patients with hepatocellular carcinoma (HCC) larger than 5 cm who underwent LLLS were comparable to those of the patients who underwent open left lateral segmentectomy. Conclusions: LLLS is safe and also feasible for hepatic tumors larger than 5 cm. For HCCs larger than 5 cm, the laparoscopic approach yields satisfying oncologic outcomes as the open approach.",
author = "Tsung-Han Yang and Chen, {Jen Lung} and Yih-Jyh Lin and Ying-Jui Chao and Yan-Shen Shan and Hui-Ping Hsu and Che-Min Su and Chou, {Chung Ching} and Yi-Ting Yen",
year = "2018",
month = "10",
day = "1",
doi = "10.1007/s00464-018-6287-9",
language = "English",
volume = "32",
pages = "4314--4320",
journal = "Surgical Endoscopy",
issn = "0930-2794",
publisher = "Springer New York",
number = "10",

}

Laparoscopic surgery for large left lateral liver tumors : safety and oncologic outcomes. / Yang, Tsung-Han; Chen, Jen Lung; Lin, Yih-Jyh; Chao, Ying-Jui; Shan, Yan-Shen; Hsu, Hui-Ping; Su, Che-Min; Chou, Chung Ching; Yen, Yi-Ting.

In: Surgical Endoscopy, Vol. 32, No. 10, 01.10.2018, p. 4314-4320.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Laparoscopic surgery for large left lateral liver tumors

T2 - safety and oncologic outcomes

AU - Yang, Tsung-Han

AU - Chen, Jen Lung

AU - Lin, Yih-Jyh

AU - Chao, Ying-Jui

AU - Shan, Yan-Shen

AU - Hsu, Hui-Ping

AU - Su, Che-Min

AU - Chou, Chung Ching

AU - Yen, Yi-Ting

PY - 2018/10/1

Y1 - 2018/10/1

N2 - Background: Although laparoscopic hepatectomy has been proven to be safe and reliable, the influence of tumor size on the feasibility of laparoscopic left lateral segmentectomy (LLLS) is unclear. We retrospectively reviewed our surgical results focusing on hepatic tumor located in the left lateral segment. Methods: From January 2003 to June 2016, patients who underwent left lateral segmentectomy were retrospectively reviewed, and data were collected on patient characteristics, peri-operative outcomes, and pathologic results. Patients with intrahepatic stone, cystic lesion, or unmeasurable tumor size were excluded. The continuous variables were compared using the Mann–Whitney U test and categorical variables using the Chi square or Fisher’s exact test. The overall and disease-free survival rates were computed using the Kaplan–Meier method and compared using the log-rank test. Results: A total of 103 patients were enrolled for analysis. Among the patients with tumors larger than 5 cm in the left lateral segment, those who underwent laparoscopic surgery had significantly shorter hospital stay and larger resection margin than those who underwent open surgery. The surgical results of the patients who underwent LLLS were not significantly different from those of the patients with tumors larger than 5 cm. Specifically, the 5-year overall survival and disease-free survival rates of the patients with hepatocellular carcinoma (HCC) larger than 5 cm who underwent LLLS were comparable to those of the patients who underwent open left lateral segmentectomy. Conclusions: LLLS is safe and also feasible for hepatic tumors larger than 5 cm. For HCCs larger than 5 cm, the laparoscopic approach yields satisfying oncologic outcomes as the open approach.

AB - Background: Although laparoscopic hepatectomy has been proven to be safe and reliable, the influence of tumor size on the feasibility of laparoscopic left lateral segmentectomy (LLLS) is unclear. We retrospectively reviewed our surgical results focusing on hepatic tumor located in the left lateral segment. Methods: From January 2003 to June 2016, patients who underwent left lateral segmentectomy were retrospectively reviewed, and data were collected on patient characteristics, peri-operative outcomes, and pathologic results. Patients with intrahepatic stone, cystic lesion, or unmeasurable tumor size were excluded. The continuous variables were compared using the Mann–Whitney U test and categorical variables using the Chi square or Fisher’s exact test. The overall and disease-free survival rates were computed using the Kaplan–Meier method and compared using the log-rank test. Results: A total of 103 patients were enrolled for analysis. Among the patients with tumors larger than 5 cm in the left lateral segment, those who underwent laparoscopic surgery had significantly shorter hospital stay and larger resection margin than those who underwent open surgery. The surgical results of the patients who underwent LLLS were not significantly different from those of the patients with tumors larger than 5 cm. Specifically, the 5-year overall survival and disease-free survival rates of the patients with hepatocellular carcinoma (HCC) larger than 5 cm who underwent LLLS were comparable to those of the patients who underwent open left lateral segmentectomy. Conclusions: LLLS is safe and also feasible for hepatic tumors larger than 5 cm. For HCCs larger than 5 cm, the laparoscopic approach yields satisfying oncologic outcomes as the open approach.

UR - http://www.scopus.com/inward/record.url?scp=85049129003&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85049129003&partnerID=8YFLogxK

U2 - 10.1007/s00464-018-6287-9

DO - 10.1007/s00464-018-6287-9

M3 - Article

C2 - 29959523

AN - SCOPUS:85049129003

VL - 32

SP - 4314

EP - 4320

JO - Surgical Endoscopy

JF - Surgical Endoscopy

SN - 0930-2794

IS - 10

ER -