Lichen planus and lichenoid dermatoses: Clinical overview and molecular basis

Christos Tziotzios, John Y.W. Lee, Timothy Brier, Ryo Saito, Chao-Kai Hsu, Kapil Bhargava, Catherine M. Stefanato, David A. Fenton, John A. McGrath

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

Deriving from the Greek word λειχήν for “tree moss” and the Latin word planus for “planar,” lichen planus is a relatively uncommon and heterogeneous cutaneous disorder that typically develops in middle-aged adults. Despite the significant clinical burden associated with the disorder, little well-conducted molecular research has been undertaken, possibly because of heterogeneity impeding consistent and confident phenotyping. The multiple variants of lichenoid disease bear overlapping clinical and pathologic features despite manifesting as distinct clinical disorders. The first article in this 2-part continuing medical education series provides a comprehensive overview of the clinical and pathologic characteristics of cutaneous lichenoid dermatoses and links these manifestations to recent advances in our understanding of the underlying pathobiology of such diseases.

Original languageEnglish
Pages (from-to)789-804
Number of pages16
JournalJournal of the American Academy of Dermatology
Volume79
Issue number5
DOIs
Publication statusPublished - 2018 Nov 1

Fingerprint

Lichen Planus
Skin Diseases
Bryophyta
Continuing Medical Education
Skin
Research

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Tziotzios, Christos ; Lee, John Y.W. ; Brier, Timothy ; Saito, Ryo ; Hsu, Chao-Kai ; Bhargava, Kapil ; Stefanato, Catherine M. ; Fenton, David A. ; McGrath, John A. / Lichen planus and lichenoid dermatoses : Clinical overview and molecular basis. In: Journal of the American Academy of Dermatology. 2018 ; Vol. 79, No. 5. pp. 789-804.
@article{28d34d91d8134680adaaeb93f988d5de,
title = "Lichen planus and lichenoid dermatoses: Clinical overview and molecular basis",
abstract = "Deriving from the Greek word λειχήν for “tree moss” and the Latin word planus for “planar,” lichen planus is a relatively uncommon and heterogeneous cutaneous disorder that typically develops in middle-aged adults. Despite the significant clinical burden associated with the disorder, little well-conducted molecular research has been undertaken, possibly because of heterogeneity impeding consistent and confident phenotyping. The multiple variants of lichenoid disease bear overlapping clinical and pathologic features despite manifesting as distinct clinical disorders. The first article in this 2-part continuing medical education series provides a comprehensive overview of the clinical and pathologic characteristics of cutaneous lichenoid dermatoses and links these manifestations to recent advances in our understanding of the underlying pathobiology of such diseases.",
author = "Christos Tziotzios and Lee, {John Y.W.} and Timothy Brier and Ryo Saito and Chao-Kai Hsu and Kapil Bhargava and Stefanato, {Catherine M.} and Fenton, {David A.} and McGrath, {John A.}",
year = "2018",
month = "11",
day = "1",
doi = "10.1016/j.jaad.2018.02.010",
language = "English",
volume = "79",
pages = "789--804",
journal = "Journal of the American Academy of Dermatology",
issn = "0190-9622",
publisher = "Mosby Inc.",
number = "5",

}

Tziotzios, C, Lee, JYW, Brier, T, Saito, R, Hsu, C-K, Bhargava, K, Stefanato, CM, Fenton, DA & McGrath, JA 2018, 'Lichen planus and lichenoid dermatoses: Clinical overview and molecular basis', Journal of the American Academy of Dermatology, vol. 79, no. 5, pp. 789-804. https://doi.org/10.1016/j.jaad.2018.02.010

Lichen planus and lichenoid dermatoses : Clinical overview and molecular basis. / Tziotzios, Christos; Lee, John Y.W.; Brier, Timothy; Saito, Ryo; Hsu, Chao-Kai; Bhargava, Kapil; Stefanato, Catherine M.; Fenton, David A.; McGrath, John A.

In: Journal of the American Academy of Dermatology, Vol. 79, No. 5, 01.11.2018, p. 789-804.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Lichen planus and lichenoid dermatoses

T2 - Clinical overview and molecular basis

AU - Tziotzios, Christos

AU - Lee, John Y.W.

AU - Brier, Timothy

AU - Saito, Ryo

AU - Hsu, Chao-Kai

AU - Bhargava, Kapil

AU - Stefanato, Catherine M.

AU - Fenton, David A.

AU - McGrath, John A.

PY - 2018/11/1

Y1 - 2018/11/1

N2 - Deriving from the Greek word λειχήν for “tree moss” and the Latin word planus for “planar,” lichen planus is a relatively uncommon and heterogeneous cutaneous disorder that typically develops in middle-aged adults. Despite the significant clinical burden associated with the disorder, little well-conducted molecular research has been undertaken, possibly because of heterogeneity impeding consistent and confident phenotyping. The multiple variants of lichenoid disease bear overlapping clinical and pathologic features despite manifesting as distinct clinical disorders. The first article in this 2-part continuing medical education series provides a comprehensive overview of the clinical and pathologic characteristics of cutaneous lichenoid dermatoses and links these manifestations to recent advances in our understanding of the underlying pathobiology of such diseases.

AB - Deriving from the Greek word λειχήν for “tree moss” and the Latin word planus for “planar,” lichen planus is a relatively uncommon and heterogeneous cutaneous disorder that typically develops in middle-aged adults. Despite the significant clinical burden associated with the disorder, little well-conducted molecular research has been undertaken, possibly because of heterogeneity impeding consistent and confident phenotyping. The multiple variants of lichenoid disease bear overlapping clinical and pathologic features despite manifesting as distinct clinical disorders. The first article in this 2-part continuing medical education series provides a comprehensive overview of the clinical and pathologic characteristics of cutaneous lichenoid dermatoses and links these manifestations to recent advances in our understanding of the underlying pathobiology of such diseases.

UR - http://www.scopus.com/inward/record.url?scp=85054563290&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85054563290&partnerID=8YFLogxK

U2 - 10.1016/j.jaad.2018.02.010

DO - 10.1016/j.jaad.2018.02.010

M3 - Review article

C2 - 30318136

AN - SCOPUS:85054563290

VL - 79

SP - 789

EP - 804

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

SN - 0190-9622

IS - 5

ER -