Life expectancy, expected years of life lost and survival of hemodialysis and peritoneal dialysis patients

Tze Wah Kao, Jenq Wen Huang, Kuan Yu Hung, Yu Yin Chang, Pau Chung Chen, Chung Jen Yen, Yung Ming Chen, Tzong Shinn Chu, Ming Shiou Wu, Tun Jun Tsai, Kwan Dun Wu, Jung-Der Wang

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18 Citations (Scopus)

Abstract

Background: Expected years of life lost (EYLL) in dialysis patients are rarely discussed. This study compared life expectancy, EYLL and survival between hemodialysis (HD) and peritoneal dialysis (PD) patients. Methods: Adults who underwent maintenance dialysis at National Taiwan University Hospital from 1995 to 2006 were followed up until December 2007. Kaplan-Meier analysis and a constant excess hazard model were used to estimate and project long-term survival. EYLL was calculated by subtracting the life expectancy of patients from that of age- and sex-matched referents. HD patients were then matched with PD patients on age, sex and diabetes mellitus (DM). Life expectancy, EYLL and survival between the 2 groups were compared. Mortality risks were determined by the Cox model. Results: Before matching, the 305 HD patients were older than the 428 PD patients (62.4 ± 13.7 vs. 53.1 ± 16.7 years; p<0.0001). More HD patients had DM (HD vs. PD, 29.2% vs. 20.6%; p=0.0072). Life expectancy and EYLL of HD patients were 8.8 and 11.5 years, compared with those of PD patients (19.9 and 7.4 years). After matching, life expectancy (p=0.790) and EYLL (p=0.793) of both groups (236 patients each) were similar. Age (adjusted hazard ratio [AHR] = 1.07; 95% confidence interval [95% CI], 1.05-1.09) and DM (AHR=3.81; 95% CI, 2.28-6.36) were independent mortality predictors. For diabetic patients who underwent HD, a better survival rate was observed (AHR=0.24; 95% CI, 0.11-0.53). Conclusions: After matching, HD and PD patients had similar life expectancy and EYLL. Survival was better for diabetic patients if they received HD.

Original languageEnglish
Pages (from-to)677-682
Number of pages6
JournalJournal of Nephrology
Volume23
Issue number6
Publication statusPublished - 2010 Nov

All Science Journal Classification (ASJC) codes

  • Nephrology

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