Abstract
Liposomes are a class of well-established drug carriers that have found numerous therapeutic applications. The success of liposomes, together with recent advancements in nanotechnology, has motivated the development of various novel liposome-like nanostructures with improved drug delivery performance. These nanostructures can be categorized into five major varieties, namely: (1) polymer-stabilized liposomes, (2) nanoparticle-stabilized liposomes, (3) core-shell lipid-polymer hybrid nanoparticles, (4) natural membrane-derived vesicles, and (5) natural membrane coated nanoparticles. They have received significant attention and have become popular drug delivery platforms. Herein, we discuss the unique strengths of these liposome-like platforms in drug delivery, with a particular emphasis on how liposome-inspired novel designs have led to improved therapeutic efficacy, and review recent progress made by each platform in advancing healthcare.
Original language | English |
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Pages (from-to) | 6569-6585 |
Number of pages | 17 |
Journal | Journal of Materials Chemistry B |
Volume | 1 |
Issue number | 48 |
DOIs | |
Publication status | Published - 2013 Dec 28 |
All Science Journal Classification (ASJC) codes
- General Chemistry
- Biomedical Engineering
- General Materials Science