Lung density standard deviations obtained using high-pitch dual-source computed tomography are valid predictors of bronchopulmonary dysplasia in preterm infants

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Abstract

Purpose: This study aimed to validate standard deviations of lung densities obtained using high-pitch dual-source computed tomography (DSCT) densitometry as indices of bronchopulmonary dysplasia (BPD) severity in premature infants. Methods: Data of preterm, late preterm group, and early term groups were evaluated. Mean and median standard deviations (SDmean, SDmedian) of CT lung density (CTLD) were calculated from CT images. Results: SDmean of CTLD in infants with severe BPD was significantly higher than that of infants without BPD (198.1 vs. 140.9, respectively; P. =. .002). Conclusions: Study results support using high-pitch DSCT for BPD diagnosis and quantitative evaluation in prematurity.

Original languageEnglish
Pages (from-to)594-600
Number of pages7
JournalClinical Imaging
Volume40
Issue number4
DOIs
Publication statusPublished - 2016 Jul 1

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Bronchopulmonary Dysplasia
Premature Infants
Tomography
Lung
Densitometry

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

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title = "Lung density standard deviations obtained using high-pitch dual-source computed tomography are valid predictors of bronchopulmonary dysplasia in preterm infants",
abstract = "Purpose: This study aimed to validate standard deviations of lung densities obtained using high-pitch dual-source computed tomography (DSCT) densitometry as indices of bronchopulmonary dysplasia (BPD) severity in premature infants. Methods: Data of preterm, late preterm group, and early term groups were evaluated. Mean and median standard deviations (SDmean, SDmedian) of CT lung density (CTLD) were calculated from CT images. Results: SDmean of CTLD in infants with severe BPD was significantly higher than that of infants without BPD (198.1 vs. 140.9, respectively; P. =. .002). Conclusions: Study results support using high-pitch DSCT for BPD diagnosis and quantitative evaluation in prematurity.",
author = "Yi-Shan Tsai and Yi-Sheng Liu and Yu-Hsiang Shih and Ming-Tsung Chuang and Yuh-Jyh Lin and Chyi-Her Lin and Yung-Chieh Lin",
year = "2016",
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day = "1",
doi = "10.1016/j.clinimag.2016.02.010",
language = "English",
volume = "40",
pages = "594--600",
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TY - JOUR

T1 - Lung density standard deviations obtained using high-pitch dual-source computed tomography are valid predictors of bronchopulmonary dysplasia in preterm infants

AU - Tsai, Yi-Shan

AU - Liu, Yi-Sheng

AU - Shih, Yu-Hsiang

AU - Chuang, Ming-Tsung

AU - Lin, Yuh-Jyh

AU - Lin, Chyi-Her

AU - Lin, Yung-Chieh

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Purpose: This study aimed to validate standard deviations of lung densities obtained using high-pitch dual-source computed tomography (DSCT) densitometry as indices of bronchopulmonary dysplasia (BPD) severity in premature infants. Methods: Data of preterm, late preterm group, and early term groups were evaluated. Mean and median standard deviations (SDmean, SDmedian) of CT lung density (CTLD) were calculated from CT images. Results: SDmean of CTLD in infants with severe BPD was significantly higher than that of infants without BPD (198.1 vs. 140.9, respectively; P. =. .002). Conclusions: Study results support using high-pitch DSCT for BPD diagnosis and quantitative evaluation in prematurity.

AB - Purpose: This study aimed to validate standard deviations of lung densities obtained using high-pitch dual-source computed tomography (DSCT) densitometry as indices of bronchopulmonary dysplasia (BPD) severity in premature infants. Methods: Data of preterm, late preterm group, and early term groups were evaluated. Mean and median standard deviations (SDmean, SDmedian) of CT lung density (CTLD) were calculated from CT images. Results: SDmean of CTLD in infants with severe BPD was significantly higher than that of infants without BPD (198.1 vs. 140.9, respectively; P. =. .002). Conclusions: Study results support using high-pitch DSCT for BPD diagnosis and quantitative evaluation in prematurity.

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