TY - JOUR
T1 - Lutein biosynthesis from microalgae — Recent advances and circular economy
AU - Leong, Yoong Kit
AU - Chang, Jo Shu
N1 - Funding Information:
The financial support received from Taiwan’s NSTC under grant number 111-2221-E-029-001 -MY3 , 110-2221-E-029-004-MY3 , 111-3116-F-006-004 , and 111-2621-M-029-002 is highly appreciated.
Funding Information:
The financial support received from Taiwan's NSTC under grant number 111-2221-E-029-001 -MY3, 110-2221-E-029-004-MY3, 111-3116-F-006-004, and 111-2621-M-029-002 is highly appreciated.
Publisher Copyright:
© 2023 The Authors
PY - 2023/5
Y1 - 2023/5
N2 - Lutein, one of the primary xanthophylls, has garnered much attention due to its numerous bioactivities, including antioxidant, eye protection as well as amelioration or prevention of diseases with a huge range of applications in feed and food, nutraceutical, pharmaceutical, and cosmeceutical industries. As a lutein producer, microalgae demonstrated immense potential as an alternative to marigold flower, the commercial source of lutein production due to numerous advantages, including a fast growth rate, no seasonal harvesting limitation, and higher lutein content and productivity. Circular economy of lutein production from microalgae can be achieved via resource recovery of abundant and low-cost byproducts or waste streams. Microalgal lutein biosynthesis is influenced by operation parameters, including temperature, light quality, salinity, and culture medium composition. Among different operation strategies, innovative two-stage cultivation approaches have been developed to maximize lutein yield from microalgae. Such strategies include a combination of different modes of nutrition (photoautotrophic, heterotrophic, mixotrophic), integration with fed-batch and/or semi-continuous cultivation mode, as well as thermal- or light-shifting operations. Furthermore, the discussion on pilot-scale studies of microalgae cultivation has been provided to give insights and bridge the gap between laboratory-scale studies and commercial-scale operations.
AB - Lutein, one of the primary xanthophylls, has garnered much attention due to its numerous bioactivities, including antioxidant, eye protection as well as amelioration or prevention of diseases with a huge range of applications in feed and food, nutraceutical, pharmaceutical, and cosmeceutical industries. As a lutein producer, microalgae demonstrated immense potential as an alternative to marigold flower, the commercial source of lutein production due to numerous advantages, including a fast growth rate, no seasonal harvesting limitation, and higher lutein content and productivity. Circular economy of lutein production from microalgae can be achieved via resource recovery of abundant and low-cost byproducts or waste streams. Microalgal lutein biosynthesis is influenced by operation parameters, including temperature, light quality, salinity, and culture medium composition. Among different operation strategies, innovative two-stage cultivation approaches have been developed to maximize lutein yield from microalgae. Such strategies include a combination of different modes of nutrition (photoautotrophic, heterotrophic, mixotrophic), integration with fed-batch and/or semi-continuous cultivation mode, as well as thermal- or light-shifting operations. Furthermore, the discussion on pilot-scale studies of microalgae cultivation has been provided to give insights and bridge the gap between laboratory-scale studies and commercial-scale operations.
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U2 - 10.1016/j.eti.2023.103097
DO - 10.1016/j.eti.2023.103097
M3 - Article
AN - SCOPUS:85150030165
SN - 2352-1864
VL - 30
JO - Environmental Technology and Innovation
JF - Environmental Technology and Innovation
M1 - 103097
ER -
