Magnetic fluid hyperthermia for living tissue with a spherical heat source

Song Yih Lin, Hsin Yi Lai, Cha'o Kuang Chen

Research output: Contribution to journalArticle

Abstract

In magnetic nanoparticle hyperthermia for cancer treatment, the diseased tissues are injected by fine magnetic particles. By operating of an alternating magnetic field, the magnetic particles are heated by magnetic hysteresis and act as localized heat sources. Literature has shown that high temperatures can damage and kill cancer cell. This article uses the thermal wave model to analyze the temperatures excess for two finite concentric spherical tissues with the heat source of Gaussian distribution during magnetic nanoparticle hyperthermia. The influences of the variations such as the relaxation time, the perfusion rate of blood, and strength of spatial heat source, upon thermal behavior are discussed. From the results, the strength of spatial heat source would not affect the time to reach temperature distribution. The blood perfusion rate has a cooling effect to adjust the tissue temperature. The thermal relaxation time can control the behavior of the thermal wave propagation and rule the propagation speed of the thermal signal.

Original languageEnglish
Pages (from-to)935-942
Number of pages8
JournalICIC Express Letters, Part B: Applications
Volume6
Issue number4
Publication statusPublished - 2015 Jan 1

All Science Journal Classification (ASJC) codes

  • Computer Science(all)

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