Male patients on peritoneal dialysis have a higher risk of sleep apnea

Yi Che Lee, Shih Yuan Hung, Hao Kuang Wang, Chi Wei Lin, Hsi Hao Wang, Min Yu Chang, Ching Fang Wu, Junne-Ming Sung, Yuan-Yow Chiou, Sheng-Hsiang Lin

Research output: Contribution to journalArticle

Abstract

Study Objectives: Peritoneal dialysis (PD) is a renal replacement therapy. One concern is whether patients on PD have a higher risk of sleep apnea (SA) due to intra-abdominal pressure increase and worsened ultrafiltration capacity. Despite this concern, to date, whether the risk of SA differs between PD, hemodialysis (HD), and groups without uremia is still uncertain. Methods: In this retrospective cohort study, data were obtained from the National Health Insurance Research Database of Taiwan. This database enrolled almost all patients on dialysis in the country. A total of 7,645 incident patients on PD and 38,225 incident patients on HD were enrolled. In addition, 38,225 patients without uremia were selected as the comparison cohort. Individuals were monitored for the occurrence of SA until 2013. Results: The results showed that patients on PD, regardless of sex, all had a higher risk of SA than non-dialysis groups. In contrast, the risk of SA in patients on HD was not significantly different from that of patients without uremia. We also compared the risk of SA between patients on PD and HD directly. The results showed that male patients on PD had a significantly higher risk of SA risk than male patients on HD. However, the risk of SA did not differ between female patients on PD and HD. Conclusions: Patients on PD should receive regular SA assessments and that an increased awareness and a higher index of suspicion for SA should be maintained in these patients, especially male patients.

Original languageEnglish
Pages (from-to)937-945
Number of pages9
JournalJournal of Clinical Sleep Medicine
Volume15
Issue number7
DOIs
Publication statusPublished - 2019 Jan 1

Fingerprint

Sleep Apnea Syndromes
Peritoneal Dialysis
Renal Dialysis
Uremia
Databases
Renal Replacement Therapy
Ultrafiltration
National Health Programs
Taiwan
Dialysis

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Neurology
  • Clinical Neurology

Cite this

Lee, Y. C., Hung, S. Y., Wang, H. K., Lin, C. W., Wang, H. H., Chang, M. Y., ... Lin, S-H. (2019). Male patients on peritoneal dialysis have a higher risk of sleep apnea. Journal of Clinical Sleep Medicine, 15(7), 937-945. https://doi.org/10.5664/jcsm.7866
Lee, Yi Che ; Hung, Shih Yuan ; Wang, Hao Kuang ; Lin, Chi Wei ; Wang, Hsi Hao ; Chang, Min Yu ; Wu, Ching Fang ; Sung, Junne-Ming ; Chiou, Yuan-Yow ; Lin, Sheng-Hsiang. / Male patients on peritoneal dialysis have a higher risk of sleep apnea. In: Journal of Clinical Sleep Medicine. 2019 ; Vol. 15, No. 7. pp. 937-945.
@article{9427ef42bd36419c9a572b4fbfed73db,
title = "Male patients on peritoneal dialysis have a higher risk of sleep apnea",
abstract = "Study Objectives: Peritoneal dialysis (PD) is a renal replacement therapy. One concern is whether patients on PD have a higher risk of sleep apnea (SA) due to intra-abdominal pressure increase and worsened ultrafiltration capacity. Despite this concern, to date, whether the risk of SA differs between PD, hemodialysis (HD), and groups without uremia is still uncertain. Methods: In this retrospective cohort study, data were obtained from the National Health Insurance Research Database of Taiwan. This database enrolled almost all patients on dialysis in the country. A total of 7,645 incident patients on PD and 38,225 incident patients on HD were enrolled. In addition, 38,225 patients without uremia were selected as the comparison cohort. Individuals were monitored for the occurrence of SA until 2013. Results: The results showed that patients on PD, regardless of sex, all had a higher risk of SA than non-dialysis groups. In contrast, the risk of SA in patients on HD was not significantly different from that of patients without uremia. We also compared the risk of SA between patients on PD and HD directly. The results showed that male patients on PD had a significantly higher risk of SA risk than male patients on HD. However, the risk of SA did not differ between female patients on PD and HD. Conclusions: Patients on PD should receive regular SA assessments and that an increased awareness and a higher index of suspicion for SA should be maintained in these patients, especially male patients.",
author = "Lee, {Yi Che} and Hung, {Shih Yuan} and Wang, {Hao Kuang} and Lin, {Chi Wei} and Wang, {Hsi Hao} and Chang, {Min Yu} and Wu, {Ching Fang} and Junne-Ming Sung and Yuan-Yow Chiou and Sheng-Hsiang Lin",
year = "2019",
month = "1",
day = "1",
doi = "10.5664/jcsm.7866",
language = "English",
volume = "15",
pages = "937--945",
journal = "Journal of Clinical Sleep Medicine",
issn = "1550-9389",
publisher = "American Academy of Sleep Medicine",
number = "7",

}

Male patients on peritoneal dialysis have a higher risk of sleep apnea. / Lee, Yi Che; Hung, Shih Yuan; Wang, Hao Kuang; Lin, Chi Wei; Wang, Hsi Hao; Chang, Min Yu; Wu, Ching Fang; Sung, Junne-Ming; Chiou, Yuan-Yow; Lin, Sheng-Hsiang.

In: Journal of Clinical Sleep Medicine, Vol. 15, No. 7, 01.01.2019, p. 937-945.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Male patients on peritoneal dialysis have a higher risk of sleep apnea

AU - Lee, Yi Che

AU - Hung, Shih Yuan

AU - Wang, Hao Kuang

AU - Lin, Chi Wei

AU - Wang, Hsi Hao

AU - Chang, Min Yu

AU - Wu, Ching Fang

AU - Sung, Junne-Ming

AU - Chiou, Yuan-Yow

AU - Lin, Sheng-Hsiang

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Study Objectives: Peritoneal dialysis (PD) is a renal replacement therapy. One concern is whether patients on PD have a higher risk of sleep apnea (SA) due to intra-abdominal pressure increase and worsened ultrafiltration capacity. Despite this concern, to date, whether the risk of SA differs between PD, hemodialysis (HD), and groups without uremia is still uncertain. Methods: In this retrospective cohort study, data were obtained from the National Health Insurance Research Database of Taiwan. This database enrolled almost all patients on dialysis in the country. A total of 7,645 incident patients on PD and 38,225 incident patients on HD were enrolled. In addition, 38,225 patients without uremia were selected as the comparison cohort. Individuals were monitored for the occurrence of SA until 2013. Results: The results showed that patients on PD, regardless of sex, all had a higher risk of SA than non-dialysis groups. In contrast, the risk of SA in patients on HD was not significantly different from that of patients without uremia. We also compared the risk of SA between patients on PD and HD directly. The results showed that male patients on PD had a significantly higher risk of SA risk than male patients on HD. However, the risk of SA did not differ between female patients on PD and HD. Conclusions: Patients on PD should receive regular SA assessments and that an increased awareness and a higher index of suspicion for SA should be maintained in these patients, especially male patients.

AB - Study Objectives: Peritoneal dialysis (PD) is a renal replacement therapy. One concern is whether patients on PD have a higher risk of sleep apnea (SA) due to intra-abdominal pressure increase and worsened ultrafiltration capacity. Despite this concern, to date, whether the risk of SA differs between PD, hemodialysis (HD), and groups without uremia is still uncertain. Methods: In this retrospective cohort study, data were obtained from the National Health Insurance Research Database of Taiwan. This database enrolled almost all patients on dialysis in the country. A total of 7,645 incident patients on PD and 38,225 incident patients on HD were enrolled. In addition, 38,225 patients without uremia were selected as the comparison cohort. Individuals were monitored for the occurrence of SA until 2013. Results: The results showed that patients on PD, regardless of sex, all had a higher risk of SA than non-dialysis groups. In contrast, the risk of SA in patients on HD was not significantly different from that of patients without uremia. We also compared the risk of SA between patients on PD and HD directly. The results showed that male patients on PD had a significantly higher risk of SA risk than male patients on HD. However, the risk of SA did not differ between female patients on PD and HD. Conclusions: Patients on PD should receive regular SA assessments and that an increased awareness and a higher index of suspicion for SA should be maintained in these patients, especially male patients.

UR - http://www.scopus.com/inward/record.url?scp=85069048995&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85069048995&partnerID=8YFLogxK

U2 - 10.5664/jcsm.7866

DO - 10.5664/jcsm.7866

M3 - Article

VL - 15

SP - 937

EP - 945

JO - Journal of Clinical Sleep Medicine

JF - Journal of Clinical Sleep Medicine

SN - 1550-9389

IS - 7

ER -