Management of gastric cancer in Asia: Resource-stratified guidelines

Lin Shen, Yan Shen Shan, Huang Ming Hu, Timothy J. Price, Bhawna Sirohi, Kun Huei Yeh, Yi Hsin Yang, Takeshi Sano, Han Kwang Yang, Xiaotian Zhang, Sook Ryun Park, Masashi Fujii, Yoon Koo Kang, Li Tzong Chen

Research output: Contribution to journalReview articlepeer-review

344 Citations (Scopus)


Gastric cancer is the fourth most common cancer globally, and is the second most common cause of death from cancer worldwide. About three-quarters of newly diagnosed cases in 2008 were from Asian countries. With a high mortality-to-incidence ratio, management of gastric cancer is challenging. We discuss evidence for optimum management of gastric cancer in aspects of screening and early detection, diagnosis, and staging; endoscopic and surgical intervention; and the concepts of perioperative, postoperative, and palliative chemotherapy and use of molecularly targeted therapy. Recommendations are formulated on the basis of the framework provided by the Breast Health Global Initiative, using the categories of basic, limited, enhanced, and maximum level. We aim to provide a stepwise strategy for management of gastric cancer applicable to different levels of health-care resources in Asian countries.

Original languageEnglish
Pages (from-to)e535-e547
JournalThe Lancet Oncology
Issue number12
Publication statusPublished - 2013 Nov

All Science Journal Classification (ASJC) codes

  • Oncology


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