Manganese induced parkinsonism: An outbreak due to an unrepaired ventilation control system in a ferromanganese smelter

J. D. Wang, C. C. Huang, Y. H. HWang, J. R. Chiang, J. M. Lin, J. S. Chen

Research output: Contribution to journalArticlepeer-review

154 Citations (Scopus)

Abstract

Several cases of parkinsonism were found in a ferromanganese smelter after the ventilation system had broken down and had not been repaired for eight months in 1985. To determine the aetiology and prevalence of parkinsonism, 132 workers were submitted to thorough medical examination and estimated air concentrations of carbon monoxide and manganese at different worksites. Only six of eight workers performing electrode fixation or welding during 1985 developed parkinsonism. They were exposed for 30 minutes each day, seven days a week, to high concentrations of air manganese (> 28.8 mg/m3). There was a consistent trend between the index of exposure to manganese and signs and symptoms exhibited by extrapyramidal systems. After repair of the ventilation system, the air concentration of manganese during electrode fixation and welding decreased to less than 4.4 mg/m3; furthermore, no new cases of parkinsonism have been observed. Workers with parkinsonism recovered partially after removal from original worksites and treatment with levodopa. It is concluded that the outbreak resulted from exposure to high concentrations of manganese fumes through the breakdown of the ventilation system.

Original languageEnglish
Pages (from-to)856-859
Number of pages4
JournalBritish Journal of Industrial Medicine
Volume46
Issue number12
DOIs
Publication statusPublished - 1989

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

Fingerprint Dive into the research topics of 'Manganese induced parkinsonism: An outbreak due to an unrepaired ventilation control system in a ferromanganese smelter'. Together they form a unique fingerprint.

Cite this