Manganese(III) acetate mediated oxidative free radical reactions between indole derivatives and 1,3-dicarbonyl compounds

An I. Tsai, Chia Hui Lin, Che Ping Chuang

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

Manganese(III) mediated oxidative free radical reactions between indole derivatives and 1,3-dicarbonyl compounds are described. In the presence of dimethyl malonate, the oxidative free radical reaction of 3-unsubstituted indoles resulted in the formation of 2-(3-oxo-2-indolylidene)malonates and these malonates can be prepared in much better yields from corresponding 3-indolecarboxylic acids. On the contrary, the oxidative free radical reaction between 3-unsubstituted indoles and 2,4-pentanedione or ethyl acetoacetate gave furo[3,2-b]indoles.{A figure is presented}.

Original languageEnglish
Pages (from-to)2381-2394
Number of pages14
JournalHeterocycles
Volume65
Issue number10
DOIs
Publication statusPublished - 2005 Oct 1

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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