'Marker-of-self' functionalization of nanoscale particles through a top-down cellular membrane coating approach

Che Ming J. Hu; Ronnie H. Fang; Brian T. Luk; Kevin N.H. Chen; Cody Carpenter; Weiwei Gao; Kang Zhang; Liangfang Zhang

doi:10.1039/c3nr00015j

'Marker-of-self' functionalization of nanoscale particles through a top-down cellular membrane coating approach

Che Ming J. Hu, Ronnie H. Fang, Brian T. Luk, Kevin N.H. Chen, Cody Carpenter, Weiwei Gao, Kang Zhang, Liangfang Zhang

Center of Applied Nanomedicine

Research output: Contribution to journal › Article › peer-review

229 Citations (Scopus)

Abstract

We investigate the 'marker-of-self' functionalization of nanoparticles through coating of natural RBC membranes. The membrane translocation approach is shown to be highly efficient and bestows nanoparticles with correctly oriented and functional immunomodulatory proteins such as CD47 at equivalent density to natural RBCs.

Original language	English
Pages (from-to)	2664-2668
Number of pages	5
Journal	Nanoscale
Volume	5
Issue number	7
DOIs	https://doi.org/10.1039/c3nr00015j
Publication status	Published - 2013

All Science Journal Classification (ASJC) codes

Materials Science(all)

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10.1039/c3nr00015j

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title = "'Marker-of-self' functionalization of nanoscale particles through a top-down cellular membrane coating approach",

abstract = "We investigate the 'marker-of-self' functionalization of nanoparticles through coating of natural RBC membranes. The membrane translocation approach is shown to be highly efficient and bestows nanoparticles with correctly oriented and functional immunomodulatory proteins such as CD47 at equivalent density to natural RBCs.",

author = "Hu, {Che Ming J.} and Fang, {Ronnie H.} and Luk, {Brian T.} and Chen, {Kevin N.H.} and Cody Carpenter and Weiwei Gao and Kang Zhang and Liangfang Zhang",

year = "2013",

doi = "10.1039/c3nr00015j",

language = "English",

volume = "5",

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journal = "Nanoscale",

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AU - Hu, Che Ming J.

AU - Fang, Ronnie H.

AU - Luk, Brian T.

AU - Chen, Kevin N.H.

AU - Carpenter, Cody

AU - Gao, Weiwei

AU - Zhang, Kang

AU - Zhang, Liangfang

PY - 2013

Y1 - 2013

N2 - We investigate the 'marker-of-self' functionalization of nanoparticles through coating of natural RBC membranes. The membrane translocation approach is shown to be highly efficient and bestows nanoparticles with correctly oriented and functional immunomodulatory proteins such as CD47 at equivalent density to natural RBCs.

AB - We investigate the 'marker-of-self' functionalization of nanoparticles through coating of natural RBC membranes. The membrane translocation approach is shown to be highly efficient and bestows nanoparticles with correctly oriented and functional immunomodulatory proteins such as CD47 at equivalent density to natural RBCs.

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DO - 10.1039/c3nr00015j

M3 - Article

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AN - SCOPUS:84886046021

SN - 2040-3364

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EP - 2668

JO - Nanoscale

JF - Nanoscale

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ER -

'Marker-of-self' functionalization of nanoscale particles through a top-down cellular membrane coating approach

Abstract

All Science Journal Classification (ASJC) codes

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