Mechanobiology and Mechanotherapy for Skin Disorders

Chao-Kai Hsu, Rei Ogawa

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Human skin is the largest organ of the body. During growth and development, the skin expands to cover the growing skeleton and soft tissues by constantly responding to the intrinsic forces of underlying skeletal growth. In addition, it responds to the extrinsic forces generated by body movements and external mechanical stimuli. Therefore, mechanobiology plays an important role in skin biology and disease pathogenesis. In this chapter, we will review the skin structure, the skin receptors for mechanical forces, and the skin disorders associated with mechanobiological dysfunction, such as keloid, scleroderma, pincer nails, bullous pemphigoid, Ehlers-Danlos syndrome (EDS), cutis laxa, skin aging, diabetic skin ulcers, leprosy, and lymphedema. Lastly, we will present a short review of mechanotherapy and its future development.

Original languageEnglish
Title of host publicationMechanobiology
Subtitle of host publicationExploitation for Medical Benefit
Publisherwiley
Pages221-237
Number of pages17
ISBN (Electronic)9781118966174
ISBN (Print)9781118966143
DOIs
Publication statusPublished - 2016 Nov 7

Fingerprint

Biophysics
Skin
Cutis Laxa
Skin Ulcer
Ehlers-Danlos Syndrome
Skin Aging
Keloid
Bullous Pemphigoid
Lymphedema
Leprosy
Nails
Growth and Development
Skin Diseases
Skeleton
Growth
Aging of materials
Tissue

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Hsu, C-K., & Ogawa, R. (2016). Mechanobiology and Mechanotherapy for Skin Disorders. In Mechanobiology: Exploitation for Medical Benefit (pp. 221-237). wiley. https://doi.org/10.1002/9781118966174.ch14
Hsu, Chao-Kai ; Ogawa, Rei. / Mechanobiology and Mechanotherapy for Skin Disorders. Mechanobiology: Exploitation for Medical Benefit. wiley, 2016. pp. 221-237
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Hsu, C-K & Ogawa, R 2016, Mechanobiology and Mechanotherapy for Skin Disorders. in Mechanobiology: Exploitation for Medical Benefit. wiley, pp. 221-237. https://doi.org/10.1002/9781118966174.ch14

Mechanobiology and Mechanotherapy for Skin Disorders. / Hsu, Chao-Kai; Ogawa, Rei.

Mechanobiology: Exploitation for Medical Benefit. wiley, 2016. p. 221-237.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Hsu C-K, Ogawa R. Mechanobiology and Mechanotherapy for Skin Disorders. In Mechanobiology: Exploitation for Medical Benefit. wiley. 2016. p. 221-237 https://doi.org/10.1002/9781118966174.ch14