Merit of integrating in situ transcriptomics and anatomical information for cell annotation and lineage construction in single-cell analyses of Populus

Ying Lan Chen, Jo Wei Allison Hsieh, Shang Che Kuo, Chung Ting Kao, Chia Chun Tung, Jhong He Yu, Tien Hsien Chang, Chuan Ku, Jianbo Xie, Deqiang Zhang, Quanzi Li, Ying Chung Jimmy Lin

Research output: Contribution to journalLetterpeer-review

2 Citations (Scopus)

Abstract

Cell type annotation and lineage construction are two of the most critical tasks conducted in the analyses of single-cell RNA sequencing (scRNA-seq). Four recent scRNA-seq studies of differentiating xylem propose four models on differentiating xylem development in Populus. The differences are mostly caused by the use of different strategies for cell type annotation and subsequent lineage interpretation. Here, we emphasize the necessity of using in situ transcriptomes and anatomical information to construct the most plausible xylem development model.

Original languageEnglish
Article number85
JournalGenome Biology
Volume25
Issue number1
DOIs
Publication statusPublished - 2024 Dec

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

Fingerprint

Dive into the research topics of 'Merit of integrating in situ transcriptomics and anatomical information for cell annotation and lineage construction in single-cell analyses of Populus'. Together they form a unique fingerprint.

Cite this