Microbial contaminations of laboratory mice and rats in Taiwan from 2004 to 2007

Chung Tiang Liang, Amy Shih, Yu Hsiu Chang, Chiung Wen Liu, Ya Tien Lee, Wei Chun Hsieh, Yuan Ling Huang, Wan Tsang Huang, Chih Hui Kuang, Kan Hung Lee, Yi Xing Zhuo, Sheng Yu Ho, Shiow Ling Liao, Yi Ying Chiu, Chieh Ning Hsu, San Chi Liang, Chun Keung Yu

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


Limited data are available on the pathogen status of contemporary rodent colonies in Taiwan. Here we summarized the rodent pathogen diagnostic records of the Taiwan National Laboratory Animal Center during a 4-y period that representing approximately 10% of the rodent colonies in Taiwan. Demand for pathogen diagnostic service increased continuously from 2004 to 2007, with a 20% increase each year. In 2007, more than 20% of the mouse colonies were positive for mouse parvovirus, mouse hepatitis virus, Theiler murine encephalomyelitis virus, and Mycoplasma pulmonis, with fewer colonies diagnosed as having infections of pneumonia virus of mice, mouse adenovirus, lymphocytic choriomeningitis virus, and reovirus. Almost 40% of tested rat colonies were positive for Mycoplasma pulmonis and rat parvovirus, with fewer colonies containing Kilham rat virus, sialodacryoadenitis virus, pneumonia virus of mice, Sendai virus, and Syphacia spp. These data provide a sound overall picture of the health status of mouse and rat colonies in Taiwan.

Original languageEnglish
Pages (from-to)381-386
Number of pages6
JournalJournal of the American Association for Laboratory Animal Science
Issue number4
Publication statusPublished - 2009 Jul

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology


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