Microcomputed tomography analysis of particular autogenous bone graft in sinus augmentation at 5 months

Differences on bone mineral density and 3D trabecular structure

Heng Li Huang, Jui Ting Hsu, Michael Y.C. Chen, Cheng Liu, Chih-Han Chang, Yu Fen Li, Kuan Ting Chen

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objectives: This study investigated the effects of gender on the three-dimensional (3D) bone mineral density (BMD) and micromorphology of the trabeculae of matured autogenous bone grafts after sinus floor augmentation, and compared them to those of adjacent native bone. Materials and methods: Ten bone biopsy samples were removed from the implant placement areas of patients who had received second-stage sinus floor augmentation, and analyzed by microcomputed tomography. BMD phantoms with two calcium hydroxyapatite densities (0. 25 and 0. 75 g/cm 3 ) were used to determine the BMD of the grafted and native bone samples. The 3D structural parameters of the trabeculae, including percentage of bone volume (bone volume/tissue volume, BV/TV), trabecular thickness (Tb. Th), trabecular number, trabecular separation, trabecular pattern factor (Tb. Pf), and structure model index, were analyzed between males and females and between grafted bone and native bone. Results: No significant gender-specific differences in BMD and 3D trabecular structure of either native or grafted bone were found (P > 0. 05). Compared to the adjacent native bone, the autogenous grafted bone exhibited lower BV/TV and Tb. Th as well as a higher Tb. Pf (P < 0. 05). Additionally, there was a weak positive correlation between the Tb. Th values of grafted and native bone (R 2 = 0. 58). Conclusions: In the maxillary sinus, autogenous grafted bone exhibited lower BV/TV, Tb. Th, and trabecular connectivity than the adjacent native bone. No significant gender-specific differences were found for either the BMD or 3D trabecular structure of grafted bone. Clinical relevance: After bone remodeling, autogenous grafted bone revealed different 3D trabecular structure as compared to native bone.

Original languageEnglish
Pages (from-to)535-542
Number of pages8
JournalClinical Oral Investigations
Volume17
Issue number2
DOIs
Publication statusPublished - 2013 Jan 1

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X-Ray Microtomography
Bone Density
Transplants
Bone and Bones
Sinus Floor Augmentation
Maxillary Sinus
Bone Remodeling

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

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title = "Microcomputed tomography analysis of particular autogenous bone graft in sinus augmentation at 5 months: Differences on bone mineral density and 3D trabecular structure",
abstract = "Objectives: This study investigated the effects of gender on the three-dimensional (3D) bone mineral density (BMD) and micromorphology of the trabeculae of matured autogenous bone grafts after sinus floor augmentation, and compared them to those of adjacent native bone. Materials and methods: Ten bone biopsy samples were removed from the implant placement areas of patients who had received second-stage sinus floor augmentation, and analyzed by microcomputed tomography. BMD phantoms with two calcium hydroxyapatite densities (0. 25 and 0. 75 g/cm 3 ) were used to determine the BMD of the grafted and native bone samples. The 3D structural parameters of the trabeculae, including percentage of bone volume (bone volume/tissue volume, BV/TV), trabecular thickness (Tb. Th), trabecular number, trabecular separation, trabecular pattern factor (Tb. Pf), and structure model index, were analyzed between males and females and between grafted bone and native bone. Results: No significant gender-specific differences in BMD and 3D trabecular structure of either native or grafted bone were found (P > 0. 05). Compared to the adjacent native bone, the autogenous grafted bone exhibited lower BV/TV and Tb. Th as well as a higher Tb. Pf (P < 0. 05). Additionally, there was a weak positive correlation between the Tb. Th values of grafted and native bone (R 2 = 0. 58). Conclusions: In the maxillary sinus, autogenous grafted bone exhibited lower BV/TV, Tb. Th, and trabecular connectivity than the adjacent native bone. No significant gender-specific differences were found for either the BMD or 3D trabecular structure of grafted bone. Clinical relevance: After bone remodeling, autogenous grafted bone revealed different 3D trabecular structure as compared to native bone.",
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Microcomputed tomography analysis of particular autogenous bone graft in sinus augmentation at 5 months : Differences on bone mineral density and 3D trabecular structure. / Huang, Heng Li; Hsu, Jui Ting; Chen, Michael Y.C.; Liu, Cheng; Chang, Chih-Han; Li, Yu Fen; Chen, Kuan Ting.

In: Clinical Oral Investigations, Vol. 17, No. 2, 01.01.2013, p. 535-542.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Microcomputed tomography analysis of particular autogenous bone graft in sinus augmentation at 5 months

T2 - Differences on bone mineral density and 3D trabecular structure

AU - Huang, Heng Li

AU - Hsu, Jui Ting

AU - Chen, Michael Y.C.

AU - Liu, Cheng

AU - Chang, Chih-Han

AU - Li, Yu Fen

AU - Chen, Kuan Ting

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N2 - Objectives: This study investigated the effects of gender on the three-dimensional (3D) bone mineral density (BMD) and micromorphology of the trabeculae of matured autogenous bone grafts after sinus floor augmentation, and compared them to those of adjacent native bone. Materials and methods: Ten bone biopsy samples were removed from the implant placement areas of patients who had received second-stage sinus floor augmentation, and analyzed by microcomputed tomography. BMD phantoms with two calcium hydroxyapatite densities (0. 25 and 0. 75 g/cm 3 ) were used to determine the BMD of the grafted and native bone samples. The 3D structural parameters of the trabeculae, including percentage of bone volume (bone volume/tissue volume, BV/TV), trabecular thickness (Tb. Th), trabecular number, trabecular separation, trabecular pattern factor (Tb. Pf), and structure model index, were analyzed between males and females and between grafted bone and native bone. Results: No significant gender-specific differences in BMD and 3D trabecular structure of either native or grafted bone were found (P > 0. 05). Compared to the adjacent native bone, the autogenous grafted bone exhibited lower BV/TV and Tb. Th as well as a higher Tb. Pf (P < 0. 05). Additionally, there was a weak positive correlation between the Tb. Th values of grafted and native bone (R 2 = 0. 58). Conclusions: In the maxillary sinus, autogenous grafted bone exhibited lower BV/TV, Tb. Th, and trabecular connectivity than the adjacent native bone. No significant gender-specific differences were found for either the BMD or 3D trabecular structure of grafted bone. Clinical relevance: After bone remodeling, autogenous grafted bone revealed different 3D trabecular structure as compared to native bone.

AB - Objectives: This study investigated the effects of gender on the three-dimensional (3D) bone mineral density (BMD) and micromorphology of the trabeculae of matured autogenous bone grafts after sinus floor augmentation, and compared them to those of adjacent native bone. Materials and methods: Ten bone biopsy samples were removed from the implant placement areas of patients who had received second-stage sinus floor augmentation, and analyzed by microcomputed tomography. BMD phantoms with two calcium hydroxyapatite densities (0. 25 and 0. 75 g/cm 3 ) were used to determine the BMD of the grafted and native bone samples. The 3D structural parameters of the trabeculae, including percentage of bone volume (bone volume/tissue volume, BV/TV), trabecular thickness (Tb. Th), trabecular number, trabecular separation, trabecular pattern factor (Tb. Pf), and structure model index, were analyzed between males and females and between grafted bone and native bone. Results: No significant gender-specific differences in BMD and 3D trabecular structure of either native or grafted bone were found (P > 0. 05). Compared to the adjacent native bone, the autogenous grafted bone exhibited lower BV/TV and Tb. Th as well as a higher Tb. Pf (P < 0. 05). Additionally, there was a weak positive correlation between the Tb. Th values of grafted and native bone (R 2 = 0. 58). Conclusions: In the maxillary sinus, autogenous grafted bone exhibited lower BV/TV, Tb. Th, and trabecular connectivity than the adjacent native bone. No significant gender-specific differences were found for either the BMD or 3D trabecular structure of grafted bone. Clinical relevance: After bone remodeling, autogenous grafted bone revealed different 3D trabecular structure as compared to native bone.

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