Microfluidic Applications of Artificial Cilia: Recent Progress, Demonstration, and Future Perspectives

Vignesh Sahadevan; Bivas Panigrahi; Chia Yuan Chen

doi:10.3390/mi13050735

Microfluidic Applications of Artificial Cilia: Recent Progress, Demonstration, and Future Perspectives

Vignesh Sahadevan, Bivas Panigrahi, Chia Yuan Chen

Department of Mechanical Engineering

Research output: Contribution to journal › Review article › peer-review

12 Citations (Scopus)

Abstract

Artificial cilia-based microfluidics is a promising alternative in lab-on-a-chip applications which provides an efficient way to manipulate fluid flow in a microfluidic environment with high precision. Additionally, it can induce favorable local flows toward practical biomedical applications. The endowment of artificial cilia with their anatomy and capabilities such as mixing, pumping, transporting, and sensing lead to advance next-generation applications including precision medicine, digital nanofluidics, and lab-on-chip systems. This review summarizes the importance and significance of the artificial cilia, delineates the recent progress in artificial cilia-based microfluidics toward microfluidic application, and provides future perspectives. The presented knowledge and insights are envisaged to pave the way for innovative advances for the research communities in miniaturization.

Original language	English
Article number	735
Journal	Micromachines
Volume	13
Issue number	5
DOIs	https://doi.org/10.3390/mi13050735
Publication status	Published - 2022 May

All Science Journal Classification (ASJC) codes

Control and Systems Engineering
Mechanical Engineering
Electrical and Electronic Engineering

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10.3390/mi13050735

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title = "Microfluidic Applications of Artificial Cilia: Recent Progress, Demonstration, and Future Perspectives",

abstract = "Artificial cilia-based microfluidics is a promising alternative in lab-on-a-chip applications which provides an efficient way to manipulate fluid flow in a microfluidic environment with high precision. Additionally, it can induce favorable local flows toward practical biomedical applications. The endowment of artificial cilia with their anatomy and capabilities such as mixing, pumping, transporting, and sensing lead to advance next-generation applications including precision medicine, digital nanofluidics, and lab-on-chip systems. This review summarizes the importance and significance of the artificial cilia, delineates the recent progress in artificial cilia-based microfluidics toward microfluidic application, and provides future perspectives. The presented knowledge and insights are envisaged to pave the way for innovative advances for the research communities in miniaturization.",

author = "Vignesh Sahadevan and Bivas Panigrahi and Chen, {Chia Yuan}",

note = "Funding Information: Funding: This study was supported through the Ministry of Science and Technology of Taiwan under Contract No. MOST 108-2221-E-006-221-MY4 (to Chia-Yuan Chen). This work would not be possible without the facility provided by the Center for Micro/Nano Science and Technology, National Cheng Kung University. This research was supported in part by Higher Education Sprout Project, Ministry of Education to the Headquarters of University Advancement at National Cheng Kung University (NCKU). Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2022",

month = may,

doi = "10.3390/mi13050735",

language = "English",

volume = "13",

journal = "Micromachines",

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AU - Panigrahi, Bivas

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N1 - Funding Information: Funding: This study was supported through the Ministry of Science and Technology of Taiwan under Contract No. MOST 108-2221-E-006-221-MY4 (to Chia-Yuan Chen). This work would not be possible without the facility provided by the Center for Micro/Nano Science and Technology, National Cheng Kung University. This research was supported in part by Higher Education Sprout Project, Ministry of Education to the Headquarters of University Advancement at National Cheng Kung University (NCKU). Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2022/5

Y1 - 2022/5

N2 - Artificial cilia-based microfluidics is a promising alternative in lab-on-a-chip applications which provides an efficient way to manipulate fluid flow in a microfluidic environment with high precision. Additionally, it can induce favorable local flows toward practical biomedical applications. The endowment of artificial cilia with their anatomy and capabilities such as mixing, pumping, transporting, and sensing lead to advance next-generation applications including precision medicine, digital nanofluidics, and lab-on-chip systems. This review summarizes the importance and significance of the artificial cilia, delineates the recent progress in artificial cilia-based microfluidics toward microfluidic application, and provides future perspectives. The presented knowledge and insights are envisaged to pave the way for innovative advances for the research communities in miniaturization.

AB - Artificial cilia-based microfluidics is a promising alternative in lab-on-a-chip applications which provides an efficient way to manipulate fluid flow in a microfluidic environment with high precision. Additionally, it can induce favorable local flows toward practical biomedical applications. The endowment of artificial cilia with their anatomy and capabilities such as mixing, pumping, transporting, and sensing lead to advance next-generation applications including precision medicine, digital nanofluidics, and lab-on-chip systems. This review summarizes the importance and significance of the artificial cilia, delineates the recent progress in artificial cilia-based microfluidics toward microfluidic application, and provides future perspectives. The presented knowledge and insights are envisaged to pave the way for innovative advances for the research communities in miniaturization.

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Microfluidic Applications of Artificial Cilia: Recent Progress, Demonstration, and Future Perspectives

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