Microfluidic chip for plasma separation from undiluted human whole blood samples using low voltage contactless dielectrophoresis and capillary force

Chia Chern Chen; Po Hsiu Lin; Chen Kuei Chung

doi:10.1039/c4lc00196f

Microfluidic chip for plasma separation from undiluted human whole blood samples using low voltage contactless dielectrophoresis and capillary force

Chia Chern Chen, Po Hsiu Lin, Chen Kuei Chung

Department of Mechanical Engineering

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

A plasma separating biochip is demonstrated using a capillary-driven contactless dielectrophoresis method with low voltage (~1 V) and high frequency induced electrostatics between red blood cells. The polarized red blood cells were aggregated and separated from plasma with a 69.8% volume separation and an 89.4% removal rate of red blood cells.

Original language	English
Pages (from-to)	1996-2001
Number of pages	6
Journal	Lab on a Chip
Volume	14
Issue number	12
DOIs	https://doi.org/10.1039/c4lc00196f
Publication status	Published - 2014 Jun 21

All Science Journal Classification (ASJC) codes

Bioengineering
Biochemistry
Chemistry(all)
Biomedical Engineering

Access to Document

10.1039/c4lc00196f

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abstract = "A plasma separating biochip is demonstrated using a capillary-driven contactless dielectrophoresis method with low voltage (~1 V) and high frequency induced electrostatics between red blood cells. The polarized red blood cells were aggregated and separated from plasma with a 69.8% volume separation and an 89.4% removal rate of red blood cells.",

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