Microfluidic chip for plasma separation from undiluted human whole blood samples using low voltage contactless dielectrophoresis and capillary force

Chia Chern Chen; Po Hsiu Lin; Chen Kuei Chung

doi:10.1039/c4lc00196f

Microfluidic chip for plasma separation from undiluted human whole blood samples using low voltage contactless dielectrophoresis and capillary force

Chia Chern Chen
, Po Hsiu Lin
, Chen Kuei Chung

Department of Mechanical Engineering

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

A plasma separating biochip is demonstrated using a capillary-driven contactless dielectrophoresis method with low voltage (~1 V) and high frequency induced electrostatics between red blood cells. The polarized red blood cells were aggregated and separated from plasma with a 69.8% volume separation and an 89.4% removal rate of red blood cells.

Original language	English
Pages (from-to)	1996-2001
Number of pages	6
Journal	Lab on a Chip
Volume	14
Issue number	12
DOIs	https://doi.org/10.1039/c4lc00196f
Publication status	Published - 2014 Jun 21

All Science Journal Classification (ASJC) codes

Bioengineering
Biochemistry
General Chemistry
Biomedical Engineering

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10.1039/c4lc00196f

Cite this

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title = "Microfluidic chip for plasma separation from undiluted human whole blood samples using low voltage contactless dielectrophoresis and capillary force",

abstract = "A plasma separating biochip is demonstrated using a capillary-driven contactless dielectrophoresis method with low voltage (\textasciitilde{}1 V) and high frequency induced electrostatics between red blood cells. The polarized red blood cells were aggregated and separated from plasma with a 69.8\% volume separation and an 89.4\% removal rate of red blood cells.",

author = "Chen, \{Chia Chern\} and Lin, \{Po Hsiu\} and Chung, \{Chen Kuei\}",

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AU - Chen, Chia Chern

AU - Lin, Po Hsiu

AU - Chung, Chen Kuei

PY - 2014/6/21

Y1 - 2014/6/21

N2 - A plasma separating biochip is demonstrated using a capillary-driven contactless dielectrophoresis method with low voltage (~1 V) and high frequency induced electrostatics between red blood cells. The polarized red blood cells were aggregated and separated from plasma with a 69.8% volume separation and an 89.4% removal rate of red blood cells.

AB - A plasma separating biochip is demonstrated using a capillary-driven contactless dielectrophoresis method with low voltage (~1 V) and high frequency induced electrostatics between red blood cells. The polarized red blood cells were aggregated and separated from plasma with a 69.8% volume separation and an 89.4% removal rate of red blood cells.

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UR - https://www.scopus.com/pages/publications/84901040110#tab=citedBy

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DO - 10.1039/c4lc00196f

M3 - Article

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AN - SCOPUS:84901040110

SN - 1473-0197

VL - 14

SP - 1996

EP - 2001

JO - Lab on a Chip

JF - Lab on a Chip

IS - 12

ER -

Microfluidic chip for plasma separation from undiluted human whole blood samples using low voltage contactless dielectrophoresis and capillary force

Abstract

All Science Journal Classification (ASJC) codes

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