Micromixer utilizing electrokinetic instability-induced shedding effect

Chang Hsien Tai, Ruey-Jen Yang, Min Zhong Huang, Chia Wei Liu, Chien Hsiung Tsai, Lung-Ming Fu

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)


This paper presents a T-shaped micromixer featuring 45° parallelogram barriers (PBs) within the mixing channel. The presented device obtains a rapid mixing of two sample fluids with conductivity ratio of 10:1 (sample concentration:running buffer concentration) by means of the electrokinetic instability-induced shedding effects which are produced when a direct current (DC) electric field of an appropriate intensity is applied. The presented device uses a single high-voltage power source to simultaneously drive and mix the sample fluids. The effectiveness of the mixer is characterized experimentally as a function of the applied electrical field intensity and the extent to which the PBs obstruct the mixing channel. The experimental results indicate that the mixing performance reaches 91% at a cross-section located 2.3 mm downstream of the T-junction when the barriers obstruct 4/5 of the channel width and an electrical field of 300 V/cm is applied. The micromixing method presented in this study provides a simple low-cost solution to mixing problems in lab-on-a-chip systems.

Original languageEnglish
Pages (from-to)4982-4990
Number of pages9
Issue number24
Publication statusPublished - 2006 Dec 1

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry

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