Miniaturized real-time oxygen detection systems integrated with optical fiber by doping ru-based fluorescence sensors

Hon Ming Fang, Song Jeng Huang, Chin Lung Yang, Kung Chia Young, Cheng Kai Yu

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

This study presents and implements a portable, real-time, miniaturized oxygen sensor and detection system. A ruthenium (Ru)-based fluorescent compound is used in conjunction with a light-emitting diode (LED) light source and a phase-shift detection system, which has fluorescent-compound-doped optical fibers and optical source excitation and reception, as well as phase detection circuits. The local oxygen concentrations correlate with the fluorescence phase shifts, which can be determined based on three approaches: an oscilloscope instrument, an integrated chip, and an amplitude-compensated detection circuit. The advantages of the proposed system include the non-consumption of fluorescence dye, no required reference substance, and fast interaction and responses, despite only a 1.4 phase difference from the optical oscilloscope measurementsystem. The proposed portable oxygen sensor has potential to offer a rapid evaluation of oxygen concentration in blood or tissues.

Original languageEnglish
Pages (from-to)117-124
Number of pages8
JournalJournal of Medical and Biological Engineering
Volume33
Issue number1
DOIs
Publication statusPublished - 2013 Mar 19

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

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