Mixed germ cell tumor presenting as intratumoral hemorrhage: report of a case originated from the pineal region.

Yu-Chang Hong, E-Jian Lee, Liang-Chao Wang, H. H. Chen, J. J. Yan, C. Y. Yu

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A 17-year-old male patient was brought to our clinic because of sudden onset of headache, vomiting, followed by transient loss of consciousness during a strenuous exercise. Neurologic examinations revealed that the patient had severe sensorimotor and brain stem dysfunction. Examinations of cranial CT and MR imaging showed a huge heterogeneously enhanced tumor originated from the pineal region with tumoral hemorrhage. The tumor markers were found to be high in AFP but not the beta-HCG and CEA. A clinical diagnosis highly suggestive of germ cell tumor was made. Prior to the planned emergency radiation therapy, he received an external ventricular drainage (EVD) and open biopsy of the tumor. Due to a postoperative complication of cerebellar hemorrhage observed 8 hours later, another maneuver was therefore required to extirpate the pineal tumor and cerebellar hematoma. The histological diagnosis proved to be a mixed germ cell tumor with tumoral hemorrhage. Spontaneous intratumoral hemorrhage in germ cell tumor of the pineal region is rare, probably due to compromised venous circulation within the tumor. The bleeding propensity, which may contribute to the formation of cerebellar hematoma, warrants a special attention when a biopsy procedure is to be performed.

Original languageEnglish
Pages (from-to)498-503
Number of pages6
JournalThe Kaohsiung journal of medical sciences
Volume15
Issue number8
Publication statusPublished - 1999 Jan 1

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Fingerprint Dive into the research topics of 'Mixed germ cell tumor presenting as intratumoral hemorrhage: report of a case originated from the pineal region.'. Together they form a unique fingerprint.

  • Cite this