Molecular markers of cancer stem cells verified in vivo

Y. S. Kim; A. M. Kaidina; J. H. Chiang; K. N. Yarygin; A. Yu Lupatov

doi:10.18097/PBMC20166203228

Molecular markers of cancer stem cells verified in vivo

Y. S. Kim, A. M. Kaidina, J. H. Chiang, K. N. Yarygin, A. Yu Lupatov

Department of Computer Science and Information Engineering

Research output: Contribution to journal › Review article › peer-review

16 Citations (Scopus)

Abstract

This systematic review aims to analyze molecular markers of cancer stem cells. Only studies that confirmed tumor-initiating capacity of this population by in vivo assay in immunodeficient mice were included. Final sample of papers that fully correspond with initial aim consists of 97 original studies. The results of their analysis reveal that markers commonly used for cancer stem cells deriving were as follows: CD133, CD44, ALDH, CD 34, CD24 and EpCAM. The review also contains description of molecular features of some cancer stem cell markers, modern approaches to cancer treatment by targeting this population and brief assessment of cancer stem cell theory development.

Original language	English
Pages (from-to)	228-238
Number of pages	11
Journal	Biomeditsinskaya Khimiya
Volume	62
Issue number	3
DOIs	https://doi.org/10.18097/PBMC20166203228
Publication status	Published - 2016

All Science Journal Classification (ASJC) codes

General Biochemistry,Genetics and Molecular Biology

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abstract = "This systematic review aims to analyze molecular markers of cancer stem cells. Only studies that confirmed tumor-initiating capacity of this population by in vivo assay in immunodeficient mice were included. Final sample of papers that fully correspond with initial aim consists of 97 original studies. The results of their analysis reveal that markers commonly used for cancer stem cells deriving were as follows: CD133, CD44, ALDH, CD 34, CD24 and EpCAM. The review also contains description of molecular features of some cancer stem cell markers, modern approaches to cancer treatment by targeting this population and brief assessment of cancer stem cell theory development.",

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AU - Kim, Y. S.

AU - Kaidina, A. M.

AU - Chiang, J. H.

AU - Yarygin, K. N.

AU - Lupatov, A. Yu

PY - 2016

Y1 - 2016

N2 - This systematic review aims to analyze molecular markers of cancer stem cells. Only studies that confirmed tumor-initiating capacity of this population by in vivo assay in immunodeficient mice were included. Final sample of papers that fully correspond with initial aim consists of 97 original studies. The results of their analysis reveal that markers commonly used for cancer stem cells deriving were as follows: CD133, CD44, ALDH, CD 34, CD24 and EpCAM. The review also contains description of molecular features of some cancer stem cell markers, modern approaches to cancer treatment by targeting this population and brief assessment of cancer stem cell theory development.

AB - This systematic review aims to analyze molecular markers of cancer stem cells. Only studies that confirmed tumor-initiating capacity of this population by in vivo assay in immunodeficient mice were included. Final sample of papers that fully correspond with initial aim consists of 97 original studies. The results of their analysis reveal that markers commonly used for cancer stem cells deriving were as follows: CD133, CD44, ALDH, CD 34, CD24 and EpCAM. The review also contains description of molecular features of some cancer stem cell markers, modern approaches to cancer treatment by targeting this population and brief assessment of cancer stem cell theory development.

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Molecular markers of cancer stem cells verified in vivo

Abstract

All Science Journal Classification (ASJC) codes

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