Monascin improves diabetes and dyslipidemia by regulating PPARγ and inhibiting lipogenesis in fructose-rich diet-induced C57BL/6 mice

Agriculture & Biology

• peroxisome proliferator-activated receptor gamma 68%
• hyperlipidemia 60%
• lipogenesis 60%
• diabetes 52%
• fructose 43%
• hyperglycemia 30%
• mice 28%
• diet 25%
• binding proteins 21%
• Monascus 17%
• hyperinsulinemia 17%
• insulin resistance 15%
• response elements 15%
• hypoglycemic agents 14%
• production economics 13%
• sterols 11%
• agonists 11%
• antagonists 10%
• therapeutics 9%
• transcription factors 9%
• fatty acids 8%
• carbohydrates 8%
• liver 7%
• cells 3%

Medicine & Life Sciences

• monascin 100%
• Lipogenesis 61%
• PPAR gamma 54%
• Dyslipidemias 48%
• Inbred C57BL Mouse 46%
• Diet 34%
• peroxisome-proliferator-activated receptor-gamma coactivator-1 20%
• Pioglitazone 15%
• Hyperglycemia 11%
• 2-chloro-5-nitrobenzanilide 9%
• Sterol Regulatory Element Binding Protein 1 8%
• Hyperinsulinism 6%
• Response Elements 6%
• Hyperlipidemias 6%
• Hypoglycemic Agents 5%
• Carbohydrates 5%
• Fatty Acids 5%
• Carrier Proteins 5%
• Blood Glucose 5%
• Insulin Resistance 5%
• Transcription Factors 4%
• Anti-Inflammatory Agents 4%
• Liver 3%
• Serum 2%
• Therapeutics 2%