Multifunctional microchip-based distillation apparatus I - Steam distillation for formaldehyde detection

Sheng Yen Hsu, Chan Chiung Liu, Chia En Yang, Lung Ming Fu

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


A multifunctional microchip-based distillation apparatus for distilling and detecting formaldehyde (CH 2 O) in food products is developed. The presented apparatus comprises a disposable microchip, a steam supply system, and a recirculating cooling water supply. The microchip is formed on PMMA substrates by laser ablation and includes a sample zone, a flash distillation zone, a cooling zone, a condensation zone, and a collection zone. In the presented method, the CH 2 O sample is placed in the microchip and is vaporized by the high-throughput vapor supply and driven through the condensed zone. The condensed CH 2 O liquid is guided into the collection zone of the microchip. Finally, the distilled CH 2 O solution is determined using an AHMT spectrometry method and a paper-based RGB (red, green and blue) intensity analysis method. A distilled efficiency is as high as 98%, when a vapor stream rate is 0.4 ml/min and a distilled time is 10 min. Moreover, both detection methods show linear relationships of the corresponding CH 2 O concentrations. The actual sample suitability of the presented multifunctional microchip-based distillation apparatus is confirmed by analyzing the CH 2 O concentrations of 21 commodities.

Original languageEnglish
Pages (from-to)94-101
Number of pages8
JournalAnalytica Chimica Acta
Publication statusPublished - 2019 Jul 25

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy

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