Multiple colonic ulcers caused by Churg-Strauss syndrome in a 15-year-old girl

T. L. Lin, C. R. Wang, M. F. Liu, P. C. Chen, Y. S. Shan, Y. T. Jin, C. H. Chien

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Churg-Strauss syndrome (CSS), or allergic granulomatous angiitis, is an uncommon vasculitic syndrome that is found mainly in middle-aged adults. We describe a 15-year-old girl with CSS, diagnosed by histological findings and characteristic clinical features. The patient experienced two episodes of catastrophic gastrointestinal vasculitis, resulting in resection of 150 cm of small intestine and right hemicolectomy. Colonoscopic examination showed multiple colonic ulcers with active bleeding. The clinical course of the patient was grave and refractory to the therapy of steroid and cytotoxic drugs. In the world literature only two patients with multiple colonic ulcers caused by CSS have been reported, and very rare cases of childhood-onset CSS have been published. We reviewed CSS in children and found that the prognosis was poorer than that in adults.

Original languageEnglish
Pages (from-to)362-364
Number of pages3
JournalClinical Rheumatology
Volume20
Issue number5
DOIs
Publication statusPublished - 2001 Jan 1

All Science Journal Classification (ASJC) codes

  • Rheumatology

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