TY - PAT
T1 - NANO-CARRIER, COMPLEX OF ANTICANCER DRUG AND NANO-CARRIER, PHARMACEUTICAL COMPOSITION THEREOF, METHOD FOR MANUFACTURING THE COMPLEX, AND METHOD FOR TREATING CANCER BY USING THE PHARMACEUTICAL COMPOSITION
AU - Yeh, Chen-Sheng
AU - Chen, Dong-Hwang
AU - Shieh, Dar-Bin
AU - Wu, Ping-Ching
PY - 2012/2/2
Y1 - 2012/2/2
N2 - The present invention relates to a nano-carrier for an anticancer drug, which comprises: a metal nanoparticle; and a polynucleotide for connecting with an anticancer drug having a pyrimidine group or a purine group, wherein the polynucleotide connects to a surface of the metal nanoparticle, and the anticancer drug binds to the polynucleotide through the pyrimidine group or the purine group. In addition, the present invention also provides a complex of an anticancer drug and a nano-carrier, a pharmaceutical composition thereof, a method for manufacturing the complex, and a method for treating a cancer by using the pharmaceutical composition.
AB - The present invention relates to a nano-carrier for an anticancer drug, which comprises: a metal nanoparticle; and a polynucleotide for connecting with an anticancer drug having a pyrimidine group or a purine group, wherein the polynucleotide connects to a surface of the metal nanoparticle, and the anticancer drug binds to the polynucleotide through the pyrimidine group or the purine group. In addition, the present invention also provides a complex of an anticancer drug and a nano-carrier, a pharmaceutical composition thereof, a method for manufacturing the complex, and a method for treating a cancer by using the pharmaceutical composition.
M3 - Patent
M1 - 8673358
ER -
