Nanoshell magnetic resonance imaging contrast agents

Chia Hao Su, Hwo Shuenn Sheu, Chia Yun Lin, Chih-Chia Huang, Yi Wei Lo, Ying Chih Pu, Jun Cheng Weng, Dar-Bin Shieh, Jyh Horng Chen, Chen-Sheng Yeh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In our studies, Au3Cu1 hollow nanostructures are believed to be the first bimetallic MR contrast agents. AU3CU 1 nanocapsules enhanced signal contrast not only in Ti-weighted imaging, but also in T2-weighted imaging at lower doses. Herein, we believe that the cooperativity originating from the form of the nanoparticles and the large surface area of the water, because of porous hollow morphology of the nanoparticle, are primarily involved. Furthermore, the amine groups on the outermost PEI polymer shell of the nanocapsules, which further provide surface modification for the attachment of biological signals, suggest great potential for use in multifunctional composite capsules as functional carriers and imaging agents. Overall, these results might lead to the creation of other non-Gd- and non-iron oxide-based bimetallic contrast agents.

Original languageEnglish
Title of host publicationDigest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC
Pages272-273
Number of pages2
DOIs
Publication statusPublished - 2007
Events20th International Microprocesses and Nanotechnology Conference, MNC 2007 - Kyoto, Japan
Duration: 2007 Nov 52007 Nov 8

Other

Others20th International Microprocesses and Nanotechnology Conference, MNC 2007
CountryJapan
CityKyoto
Period07-11-0507-11-08

Fingerprint

Nanoshells
Magnetic resonance
Nanocapsules
Imaging techniques
Nanoparticles
Polyetherimides
Surface treatment
Amines
Nanostructures
Oxides
Composite materials
Polymers
Water

All Science Journal Classification (ASJC) codes

  • Hardware and Architecture
  • Electrical and Electronic Engineering

Cite this

Su, C. H., Sheu, H. S., Lin, C. Y., Huang, C-C., Lo, Y. W., Pu, Y. C., ... Yeh, C-S. (2007). Nanoshell magnetic resonance imaging contrast agents. In Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC (pp. 272-273). [4456209] https://doi.org/10.1109/IMNC.2007.4456209
Su, Chia Hao ; Sheu, Hwo Shuenn ; Lin, Chia Yun ; Huang, Chih-Chia ; Lo, Yi Wei ; Pu, Ying Chih ; Weng, Jun Cheng ; Shieh, Dar-Bin ; Chen, Jyh Horng ; Yeh, Chen-Sheng. / Nanoshell magnetic resonance imaging contrast agents. Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC. 2007. pp. 272-273
@inproceedings{8090693895554998927254eee21d75c9,
title = "Nanoshell magnetic resonance imaging contrast agents",
abstract = "In our studies, Au3Cu1 hollow nanostructures are believed to be the first bimetallic MR contrast agents. AU3CU 1 nanocapsules enhanced signal contrast not only in Ti-weighted imaging, but also in T2-weighted imaging at lower doses. Herein, we believe that the cooperativity originating from the form of the nanoparticles and the large surface area of the water, because of porous hollow morphology of the nanoparticle, are primarily involved. Furthermore, the amine groups on the outermost PEI polymer shell of the nanocapsules, which further provide surface modification for the attachment of biological signals, suggest great potential for use in multifunctional composite capsules as functional carriers and imaging agents. Overall, these results might lead to the creation of other non-Gd- and non-iron oxide-based bimetallic contrast agents.",
author = "Su, {Chia Hao} and Sheu, {Hwo Shuenn} and Lin, {Chia Yun} and Chih-Chia Huang and Lo, {Yi Wei} and Pu, {Ying Chih} and Weng, {Jun Cheng} and Dar-Bin Shieh and Chen, {Jyh Horng} and Chen-Sheng Yeh",
year = "2007",
doi = "10.1109/IMNC.2007.4456209",
language = "English",
isbn = "4990247248",
pages = "272--273",
booktitle = "Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC",

}

Su, CH, Sheu, HS, Lin, CY, Huang, C-C, Lo, YW, Pu, YC, Weng, JC, Shieh, D-B, Chen, JH & Yeh, C-S 2007, Nanoshell magnetic resonance imaging contrast agents. in Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC., 4456209, pp. 272-273, s20th International Microprocesses and Nanotechnology Conference, MNC 2007, Kyoto, Japan, 07-11-05. https://doi.org/10.1109/IMNC.2007.4456209

Nanoshell magnetic resonance imaging contrast agents. / Su, Chia Hao; Sheu, Hwo Shuenn; Lin, Chia Yun; Huang, Chih-Chia; Lo, Yi Wei; Pu, Ying Chih; Weng, Jun Cheng; Shieh, Dar-Bin; Chen, Jyh Horng; Yeh, Chen-Sheng.

Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC. 2007. p. 272-273 4456209.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - Nanoshell magnetic resonance imaging contrast agents

AU - Su, Chia Hao

AU - Sheu, Hwo Shuenn

AU - Lin, Chia Yun

AU - Huang, Chih-Chia

AU - Lo, Yi Wei

AU - Pu, Ying Chih

AU - Weng, Jun Cheng

AU - Shieh, Dar-Bin

AU - Chen, Jyh Horng

AU - Yeh, Chen-Sheng

PY - 2007

Y1 - 2007

N2 - In our studies, Au3Cu1 hollow nanostructures are believed to be the first bimetallic MR contrast agents. AU3CU 1 nanocapsules enhanced signal contrast not only in Ti-weighted imaging, but also in T2-weighted imaging at lower doses. Herein, we believe that the cooperativity originating from the form of the nanoparticles and the large surface area of the water, because of porous hollow morphology of the nanoparticle, are primarily involved. Furthermore, the amine groups on the outermost PEI polymer shell of the nanocapsules, which further provide surface modification for the attachment of biological signals, suggest great potential for use in multifunctional composite capsules as functional carriers and imaging agents. Overall, these results might lead to the creation of other non-Gd- and non-iron oxide-based bimetallic contrast agents.

AB - In our studies, Au3Cu1 hollow nanostructures are believed to be the first bimetallic MR contrast agents. AU3CU 1 nanocapsules enhanced signal contrast not only in Ti-weighted imaging, but also in T2-weighted imaging at lower doses. Herein, we believe that the cooperativity originating from the form of the nanoparticles and the large surface area of the water, because of porous hollow morphology of the nanoparticle, are primarily involved. Furthermore, the amine groups on the outermost PEI polymer shell of the nanocapsules, which further provide surface modification for the attachment of biological signals, suggest great potential for use in multifunctional composite capsules as functional carriers and imaging agents. Overall, these results might lead to the creation of other non-Gd- and non-iron oxide-based bimetallic contrast agents.

UR - http://www.scopus.com/inward/record.url?scp=47349095397&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=47349095397&partnerID=8YFLogxK

U2 - 10.1109/IMNC.2007.4456209

DO - 10.1109/IMNC.2007.4456209

M3 - Conference contribution

SN - 4990247248

SN - 9784990247249

SP - 272

EP - 273

BT - Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC

ER -

Su CH, Sheu HS, Lin CY, Huang C-C, Lo YW, Pu YC et al. Nanoshell magnetic resonance imaging contrast agents. In Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC. 2007. p. 272-273. 4456209 https://doi.org/10.1109/IMNC.2007.4456209