Abstract
Rationale: Xanthogranulomatous inflammation (XGI) is a rare inflammatory process, which mostly affects the kidney and gallbladder. It usually simulates an aggressive neoplastic process. Occurrences in the neck are extremely rare and would usually be associated with a preexisting cyst or glandular tissues. Patient concerns: A 49-year-old diabetic patient presented with a right painful neck mass for a week. The pretreatment computed tomography (CT) imaging with contrast demonstrated a huge ill-defined heterogeneous-enhanced lesion abutting surrounding musculatures and great vessels. Both fine needle aspiration (FNA) and ultrasound-guided core biopsy of the neck mass showed inflammatory cells only. Diagnoses: Histologic evaluation found granulation tissue with histiocytes and occasional Touton giant cells confirming the diagnosis of xanthogranuloma. Interventions: Open excisional biopsy demonstrated a yellowish mass-like lesion with abscess inside. Outcomes: The patient recovered from the disease without posttreatment comorbidities. Lessons: This case highlights the need for physicians to maintain awareness of this clinical entity and delayed- or overtreatment should be avoided in these patients due to preoperative ambiguous diagnosis.
| Original language | English |
|---|---|
| Article number | e12615 |
| Journal | Medicine (United States) |
| Volume | 97 |
| Issue number | 40 |
| DOIs | |
| Publication status | Published - 2018 Oct 1 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
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Neck xanthogranuloma mimicking malignancy in a patient with diabetes mellitus : A case report and literature review. / Chen, Tzu Pai; Yi, Wan Ling; Liu, Chiang Shin; Lin, Yu Hsuan.
In: Medicine (United States), Vol. 97, No. 40, e12615, 01.10.2018.Research output: Contribution to journal › Review article
TY - JOUR
T1 - Neck xanthogranuloma mimicking malignancy in a patient with diabetes mellitus
T2 - A case report and literature review
AU - Chen, Tzu Pai
AU - Yi, Wan Ling
AU - Liu, Chiang Shin
AU - Lin, Yu Hsuan
PY - 2018/10/1
Y1 - 2018/10/1
N2 - Rationale: Xanthogranulomatous inflammation (XGI) is a rare inflammatory process, which mostly affects the kidney and gallbladder. It usually simulates an aggressive neoplastic process. Occurrences in the neck are extremely rare and would usually be associated with a preexisting cyst or glandular tissues. Patient concerns: A 49-year-old diabetic patient presented with a right painful neck mass for a week. The pretreatment computed tomography (CT) imaging with contrast demonstrated a huge ill-defined heterogeneous-enhanced lesion abutting surrounding musculatures and great vessels. Both fine needle aspiration (FNA) and ultrasound-guided core biopsy of the neck mass showed inflammatory cells only. Diagnoses: Histologic evaluation found granulation tissue with histiocytes and occasional Touton giant cells confirming the diagnosis of xanthogranuloma. Interventions: Open excisional biopsy demonstrated a yellowish mass-like lesion with abscess inside. Outcomes: The patient recovered from the disease without posttreatment comorbidities. Lessons: This case highlights the need for physicians to maintain awareness of this clinical entity and delayed- or overtreatment should be avoided in these patients due to preoperative ambiguous diagnosis.
AB - Rationale: Xanthogranulomatous inflammation (XGI) is a rare inflammatory process, which mostly affects the kidney and gallbladder. It usually simulates an aggressive neoplastic process. Occurrences in the neck are extremely rare and would usually be associated with a preexisting cyst or glandular tissues. Patient concerns: A 49-year-old diabetic patient presented with a right painful neck mass for a week. The pretreatment computed tomography (CT) imaging with contrast demonstrated a huge ill-defined heterogeneous-enhanced lesion abutting surrounding musculatures and great vessels. Both fine needle aspiration (FNA) and ultrasound-guided core biopsy of the neck mass showed inflammatory cells only. Diagnoses: Histologic evaluation found granulation tissue with histiocytes and occasional Touton giant cells confirming the diagnosis of xanthogranuloma. Interventions: Open excisional biopsy demonstrated a yellowish mass-like lesion with abscess inside. Outcomes: The patient recovered from the disease without posttreatment comorbidities. Lessons: This case highlights the need for physicians to maintain awareness of this clinical entity and delayed- or overtreatment should be avoided in these patients due to preoperative ambiguous diagnosis.
UR - http://www.scopus.com/inward/record.url?scp=85054426265&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85054426265&partnerID=8YFLogxK
U2 - 10.1097/MD.0000000000012615
DO - 10.1097/MD.0000000000012615
M3 - Review article
C2 - 30290633
AN - SCOPUS:85054426265
VL - 97
JO - Medicine (United States)
JF - Medicine (United States)
SN - 0025-7974
IS - 40
M1 - e12615
ER -