Neonatal Adrenoleukodystrophy Presenting With Seizure at Birth

A Case Report and Review of the Literature

Ying Chao Chang, Chao-Ching Huang, Song Chei Huang, Fang Chih Hung

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Neonatal seizures are critical conditions because they are usually related to significant illnesses that require a specific therapy. Antepartum and peripartum seizures are very rare, and represent signs of prenatal-onset neurologic dysfunction. A review of the literature revealed that the main etiologies include severe brain malformations, multiple anomalies, and metabolic encephalopathy. A high incidence of early fatality and serious neurologic sequelae were noted. To our knowledge, this is the first case report of neonatal adrenoleukodystrophy presenting with seizure at birth. These very-early-onset seizures may require unique diagnostic and therapeutic considerations, in contrast with the later onset of seizures in neonates.

Original languageEnglish
Pages (from-to)137-139
Number of pages3
JournalPediatric Neurology
Volume38
Issue number2
DOIs
Publication statusPublished - 2008 Feb 1

Fingerprint

Peroxisomal Disorders
Seizures
Parturition
Metabolic Brain Diseases
Peripartum Period
Neurologic Manifestations
Nervous System
Incidence
Brain
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

Cite this

Chang, Ying Chao ; Huang, Chao-Ching ; Huang, Song Chei ; Hung, Fang Chih. / Neonatal Adrenoleukodystrophy Presenting With Seizure at Birth : A Case Report and Review of the Literature. In: Pediatric Neurology. 2008 ; Vol. 38, No. 2. pp. 137-139.
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Neonatal Adrenoleukodystrophy Presenting With Seizure at Birth : A Case Report and Review of the Literature. / Chang, Ying Chao; Huang, Chao-Ching; Huang, Song Chei; Hung, Fang Chih.

In: Pediatric Neurology, Vol. 38, No. 2, 01.02.2008, p. 137-139.

Research output: Contribution to journalArticle

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