Abstract
This work reports cascade cyclization between 1-allenyl-2-alkynylbenzenes and nitrosoarenes. When these two components reacted alone under N2, N,O-functionalized indane-fused isoxazolidines 3 were obtained selectively. DFT calculations verify that this reaction sequence involves unprecedented nitrone/alkyne cycloadditions, followed by diradical rearrangement.
Original language | English |
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Pages (from-to) | 82-86 |
Number of pages | 5 |
Journal | Organic Letters |
Volume | 25 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2023 Jan 13 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry