Non-polymer coated Fe3O4 aqueous dispersion with NH3+-surface modification as new magnetite nanoparticles and their biomedical applications

F. Y. Cheng, D. B. Shieh, C. S. Yeh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Well-dispersed Fe3O4 nanoparticles were synthesized using chemical coprecipitation and the addition of organic acid as adherent in an aqueous solution. The resulting iron oxide particles were manipulated as small as 6 nm diameter in size. The nanoparticles exhibit cationic surface mostly decorated with terminal -NH3+. The in vitro cytotoxicity test revealed excellent biocompatibility to further explore for their potential in vivo applications. NMR measurements showed significantly reduced water proton relaxation times T1 and T2. The MR images of the nanoparticles in water and serum were then investigated using 1.5T clinical MR imager.

Original languageEnglish
Title of host publication2005 5th IEEE Conference on Nanotechnology
PublisherIEEE Computer Society
Pages620-623
Number of pages4
ISBN (Print)0780391993, 9780780391994
DOIs
Publication statusPublished - 2005
Event2005 5th IEEE Conference on Nanotechnology - Nagoya, Japan
Duration: 2005 Jul 112005 Jul 15

Publication series

Name2005 5th IEEE Conference on Nanotechnology
Volume2

Other

Other2005 5th IEEE Conference on Nanotechnology
CountryJapan
CityNagoya
Period05-07-1105-07-15

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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