TY - JOUR
T1 - Nonlinear conductance-volume relationship for murine conductance catheter measurement system
AU - Wei, Chia Ling
AU - Valvano, Jonathan W.
AU - Feldman, Marc D.
AU - Pearce, John A.
N1 - Funding Information:
Manuscript received September 26, 2004; revised March 6, 2005. This work was supported in part by the American Heart Association Texas Affiliate under Grant 0255812Y, in part by the National Institutes of Health under Grant HL-67475, and in part by Millar Instruments, Inc., Houston, Texas. Asterisk indicates corresponding author. *C.-L. Wei was with the Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX 78712 USA. She is now with Silicon Laboratories Inc., 4635 Boston Lane, Austin, TX 78735 USA (e-mail: [email protected]).
PY - 2005/10
Y1 - 2005/10
N2 - The conductance catheter system is a tool to determine instantaneous left ventricular volume in vivo by converting measured conductance to volume. The currently adopted conductance-to-volume conversion equation was proposed by Baan, and the accuracy of this equation is limited by the assumption of a linear conductance-volume relationship. The electric field generated by a conductance catheter is nonuniform, which results in a nonlinear relationship between conductance and volume. This paper investigates this nonlinear relationship and proposes a new nonlinear conductance-to-volume conversion equation. The proposed nonlinear equation uses a single empirically determined calibration coefficient, derived from independently measured stroke volume. In vitro experiments and numerical model simulations were performed to verify and validate the proposed equation.
AB - The conductance catheter system is a tool to determine instantaneous left ventricular volume in vivo by converting measured conductance to volume. The currently adopted conductance-to-volume conversion equation was proposed by Baan, and the accuracy of this equation is limited by the assumption of a linear conductance-volume relationship. The electric field generated by a conductance catheter is nonuniform, which results in a nonlinear relationship between conductance and volume. This paper investigates this nonlinear relationship and proposes a new nonlinear conductance-to-volume conversion equation. The proposed nonlinear equation uses a single empirically determined calibration coefficient, derived from independently measured stroke volume. In vitro experiments and numerical model simulations were performed to verify and validate the proposed equation.
UR - http://www.scopus.com/inward/record.url?scp=26444584329&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=26444584329&partnerID=8YFLogxK
U2 - 10.1109/TBME.2005.856029
DO - 10.1109/TBME.2005.856029
M3 - Article
C2 - 16235651
AN - SCOPUS:26444584329
SN - 0018-9294
VL - 52
SP - 1654
EP - 1661
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
IS - 10
ER -