Novel 10-Bit Impedance-To-Digital Converter for Electrochemical Impedance Spectroscopy Measurements

Tse An Chen, Wen Jui Wu, Chia Ling Wei, Robert B. Darling, Bin Da Liu

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Electrochemical impedance spectroscopy (EIS) is a widely used technique in biomedical and chemical analysis. A novel 10-bit impedance-To-digital converter (IDC), which can measure and directly convert the magnitude and phase of impedance to digital codes, is proposed for the EIS measurement system. The proposed IDC is composed of a magnitude-To-digital converter (MDC) and a phase-To-digital converter (PDC). The proposed IDC was designed and fabricated using a 0.35 \mu\text{m} 2P4M mixed-signal polycide process, and the core area is only 0.07 mm2. Moreover, it can work over a very wide frequency range (0.1 mHz-100 kHz), and has excellent accuracy. According to the measured results, the DNL of the MDC is within-0.3/+0.3 LSB, and the INL is around-3/+1 LSB. Moreover, an EIS measurement system, which is composed of the proposed IDC chip and some other commercial chips, is built to measure ZoBell's and melatonin solutions for validating the function of the proposed IDC.

Original languageEnglish
Article number7740023
Pages (from-to)370-379
Number of pages10
JournalIEEE transactions on biomedical circuits and systems
Issue number2
Publication statusPublished - 2017 Apr

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Electrical and Electronic Engineering

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