Novel arylhydrazone-conjugated gold nanoparticles with DNA-cleaving ability

The first DNA-nicking nanomaterial

Ming Hua Hsu, Thainashmuthu Josephrajan, Chen-Sheng Yeh, Dar-Bin Shieh, Wu-Chou Su, Ru Hwu Jih

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Arylhydrazones were linked onto gold nanoparticles through the poly(ethylene glycol) spacer to produce a new type of photoinduced DNA-cleaving nanomaterials with great potency.

Original languageEnglish
Pages (from-to)1709-1712
Number of pages4
JournalBioconjugate Chemistry
Volume18
Issue number6
DOIs
Publication statusPublished - 2007 Nov 1

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Ethylene Glycol
Nanostructures
Nanostructured materials
Gold
Nanoparticles
Polyethylene glycols
DNA

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Organic Chemistry
  • Clinical Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

Cite this

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title = "Novel arylhydrazone-conjugated gold nanoparticles with DNA-cleaving ability: The first DNA-nicking nanomaterial",
abstract = "Arylhydrazones were linked onto gold nanoparticles through the poly(ethylene glycol) spacer to produce a new type of photoinduced DNA-cleaving nanomaterials with great potency.",
author = "Hsu, {Ming Hua} and Thainashmuthu Josephrajan and Chen-Sheng Yeh and Dar-Bin Shieh and Wu-Chou Su and Jih, {Ru Hwu}",
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Novel arylhydrazone-conjugated gold nanoparticles with DNA-cleaving ability : The first DNA-nicking nanomaterial. / Hsu, Ming Hua; Josephrajan, Thainashmuthu; Yeh, Chen-Sheng; Shieh, Dar-Bin; Su, Wu-Chou; Jih, Ru Hwu.

In: Bioconjugate Chemistry, Vol. 18, No. 6, 01.11.2007, p. 1709-1712.

Research output: Contribution to journalArticle

TY - JOUR

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AU - Hsu, Ming Hua

AU - Josephrajan, Thainashmuthu

AU - Yeh, Chen-Sheng

AU - Shieh, Dar-Bin

AU - Su, Wu-Chou

AU - Jih, Ru Hwu

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