Novel synthesis of PEG/polycation block copolymers possessing a reactive PEG end group for high performance gene targeting

Y. Nagasaki; D. Wakebayash; Y. Akiyama; A. Harada; K. Kataoka

Novel synthesis of PEG/polycation block copolymers possessing a reactive PEG end group for high performance gene targeting

Y. Nagasaki
, D. Wakebayash
, Y. Akiyama
, A. Harada
, K. Kataoka

Center of Applied Nanomedicine

Research output: Contribution to journal › Conference article › peer-review

4 Citations (Scopus)

Abstract

Two kinds of block copolymers, acetal-poly(ethylene glycol)/poly[2-N,N-dimethylamino) ethyl methacrylate] (acetal-PEG/PAMA) and acetal-PEG/poly(ethylene imine) (acetal-PEG/PEI) were synthesized via a heterotelechelic PEG macroinitiator technique. The synthesis of these copolymers constitute a novel way of constructing reactive polyion complex (PIC) micelles with an aldehyde functionality on their outer layer.

Original language	English
Pages (from-to)	1649-1650
Number of pages	2
Journal	American Chemical Society, Polymer Preprints, Division of Polymer Chemistry
Volume	41
Issue number	2
Publication status	Published - 2000 Aug
Event	Washington,DC. Meeting - Washington, DC, USA Duration: 2000 Aug 20 → 2000 Aug 24

All Science Journal Classification (ASJC) codes

Polymers and Plastics

Cite this

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title = "Novel synthesis of PEG/polycation block copolymers possessing a reactive PEG end group for high performance gene targeting",

abstract = "Two kinds of block copolymers, acetal-poly(ethylene glycol)/poly[2-N,N-dimethylamino) ethyl methacrylate] (acetal-PEG/PAMA) and acetal-PEG/poly(ethylene imine) (acetal-PEG/PEI) were synthesized via a heterotelechelic PEG macroinitiator technique. The synthesis of these copolymers constitute a novel way of constructing reactive polyion complex (PIC) micelles with an aldehyde functionality on their outer layer.",

author = "Y. Nagasaki and D. Wakebayash and Y. Akiyama and A. Harada and K. Kataoka",

year = "2000",

month = aug,

language = "English",

volume = "41",

pages = "1649--1650",

journal = "American Chemical Society, Polymer Preprints, Division of Polymer Chemistry",

issn = "0032-3934",

number = "2",

note = "Washington,DC. Meeting ; Conference date: 20-08-2000 Through 24-08-2000",

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Novel synthesis of PEG/polycation block copolymers possessing a reactive PEG end group for high performance gene targeting. / Nagasaki, Y.; Wakebayash, D.; Akiyama, Y. et al.
In: American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, Vol. 41, No. 2, 08.2000, p. 1649-1650.

Research output: Contribution to journal › Conference article › peer-review

TY - JOUR

T1 - Novel synthesis of PEG/polycation block copolymers possessing a reactive PEG end group for high performance gene targeting

AU - Nagasaki, Y.

AU - Wakebayash, D.

AU - Akiyama, Y.

AU - Harada, A.

AU - Kataoka, K.

PY - 2000/8

Y1 - 2000/8

N2 - Two kinds of block copolymers, acetal-poly(ethylene glycol)/poly[2-N,N-dimethylamino) ethyl methacrylate] (acetal-PEG/PAMA) and acetal-PEG/poly(ethylene imine) (acetal-PEG/PEI) were synthesized via a heterotelechelic PEG macroinitiator technique. The synthesis of these copolymers constitute a novel way of constructing reactive polyion complex (PIC) micelles with an aldehyde functionality on their outer layer.

AB - Two kinds of block copolymers, acetal-poly(ethylene glycol)/poly[2-N,N-dimethylamino) ethyl methacrylate] (acetal-PEG/PAMA) and acetal-PEG/poly(ethylene imine) (acetal-PEG/PEI) were synthesized via a heterotelechelic PEG macroinitiator technique. The synthesis of these copolymers constitute a novel way of constructing reactive polyion complex (PIC) micelles with an aldehyde functionality on their outer layer.

UR - https://www.scopus.com/pages/publications/6744266664

UR - https://www.scopus.com/pages/publications/6744266664#tab=citedBy

M3 - Conference article

AN - SCOPUS:6744266664

SN - 0032-3934

VL - 41

SP - 1649

EP - 1650

JO - American Chemical Society, Polymer Preprints, Division of Polymer Chemistry

JF - American Chemical Society, Polymer Preprints, Division of Polymer Chemistry

IS - 2

T2 - Washington,DC. Meeting

Y2 - 20 August 2000 through 24 August 2000

ER -

Novel synthesis of PEG/polycation block copolymers possessing a reactive PEG end group for high performance gene targeting

Abstract

All Science Journal Classification (ASJC) codes

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