Novel terpenoids from Calocedrus macrolepis var. formosana

Chin Lin Hsieh, Mei Hwei Tseng, Ryh Nan Pan, Jang Yang Chang, Ching Chuan Kuo, Tzong Huei Lee, Yueh Hsiung Kuo

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Calocetriol (1), diacetylcalocediol (2), and ferrugimenthenol (3) were isolated from the bark of Calocedrus macrolepis var. formosana. Among them, 1 and 2 are secoabietane-type diterpenoids, and 3, with a novel C 20-C 10 skeleton, is classified as a meroterpenoid. The structures of 1-3 were elucidated by spectroscopic analyses, and their biological activities were also evaluated. Compound 3 exhibited significant cytotoxic activity against human oral epidermoid carcinoma KB cells with an IC 50 value of 9.0±0.1 μM.

Original languageEnglish
Pages (from-to)1901-1907
Number of pages7
JournalChemistry and Biodiversity
Issue number10
Publication statusPublished - 2011 Oct 1

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Molecular Medicine
  • Molecular Biology

Fingerprint Dive into the research topics of 'Novel terpenoids from Calocedrus macrolepis var. formosana'. Together they form a unique fingerprint.

Cite this