Nuclear topology, epigenetics, and keratinocyte differentiation

Michael W. Hughes; Wange Lu; Cheng Ming Chuong

doi:10.1038/jid.2013.261

Nuclear topology, epigenetics, and keratinocyte differentiation

Michael W. Hughes, Wange Lu, Cheng Ming Chuong

Institute of Clinical Medicine

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Recent progress in epigenetics reveals dynamic chromatin interactions in the nucleus during development, regeneration, reprogramming, and in disease. Higher-order chromatin organization is manifested as changes in the topological distribution of eu-/heterochromatin and in nuclear morphology. We are now able to gain new knowledge about these changes at the genomic level.

Original language	English
Pages (from-to)	2130-2133
Number of pages	4
Journal	Journal of Investigative Dermatology
Volume	133
Issue number	9
DOIs	https://doi.org/10.1038/jid.2013.261
Publication status	Published - 2013 Sept

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Dermatology
Cell Biology

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10.1038/jid.2013.261

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title = "Nuclear topology, epigenetics, and keratinocyte differentiation",

abstract = "Recent progress in epigenetics reveals dynamic chromatin interactions in the nucleus during development, regeneration, reprogramming, and in disease. Higher-order chromatin organization is manifested as changes in the topological distribution of eu-/heterochromatin and in nuclear morphology. We are now able to gain new knowledge about these changes at the genomic level.",

author = "Hughes, {Michael W.} and Wange Lu and Chuong, {Cheng Ming}",

year = "2013",

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AU - Hughes, Michael W.

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AB - Recent progress in epigenetics reveals dynamic chromatin interactions in the nucleus during development, regeneration, reprogramming, and in disease. Higher-order chromatin organization is manifested as changes in the topological distribution of eu-/heterochromatin and in nuclear morphology. We are now able to gain new knowledge about these changes at the genomic level.

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JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

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ER -

Nuclear topology, epigenetics, and keratinocyte differentiation

Abstract

All Science Journal Classification (ASJC) codes

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