Abstract
A nucleic acid cleavage complex is disclosed, which includes: a nanoparticle, a nucleic acid cleavage reagent, and a polynucleotide chain specifically recognizing a sequence of a target nucleic acid and having a first terminal and a second terminal opposite to the first terminal, wherein the first terminal is connected to the nanoparticle, the second terminal is connected to the nucleic acid cleavage reagent,and the first terminal sequence and the second terminal sequence are base-paired to make the polynucleotide chain form a hairpin.
| Translated title of the contribution | 核酸切割複合物及其使用方法 |
|---|---|
| Original language | English |
| Patent number | 8574893 |
| Publication status | Published - 2012 May 17 |