Numerical simulation and optimal design on a new dielectrophoretic-based cytosorter

Tzong-Shyng Leu, Yao Jen Kuo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper is an attempt to investigate, through numerical simulation and optimization methods, the optimal design of dielectrophoretic (DEP) ctyosorters under certain constrains. DEP electrodes is designed to maximize the sorting resolution of a cytosorter, defined as the degree of (bio)particle deflection. In order to obtain the maximal particle deflection, different non-uniform electrical fields are produced by combinations of electrodes with different lengths. The findings of numerical simulation indicate that the design of electrodes near Xf/L= 0.283 and Xb/L=0.25 can maximize the particle deflection in the current flow sorter design constraints. In this study, an optimization method to accelerate the cytosorter design process is also presented. By using the numerical simulation and the optimization method, the cases for optimal design processes can reduce from 465 to 50 and still get a reasonable result.

Original languageEnglish
Title of host publicationProceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
Pages556-560
Number of pages5
DOIs
Publication statusPublished - 2007
Event2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 - Bangkok, Thailand
Duration: 2007 Jan 162007 Jan 19

Other

Other2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
CountryThailand
CityBangkok
Period07-01-1607-01-19

Fingerprint

Electrodes
Computer simulation
Sorting
Optimal design

All Science Journal Classification (ASJC) codes

  • Computer Networks and Communications
  • Computer Science Applications
  • Electrical and Electronic Engineering

Cite this

Leu, T-S., & Kuo, Y. J. (2007). Numerical simulation and optimal design on a new dielectrophoretic-based cytosorter. In Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 (pp. 556-560). [4160383] https://doi.org/10.1109/NEMS.2007.352080
Leu, Tzong-Shyng ; Kuo, Yao Jen. / Numerical simulation and optimal design on a new dielectrophoretic-based cytosorter. Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007. 2007. pp. 556-560
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Leu, T-S & Kuo, YJ 2007, Numerical simulation and optimal design on a new dielectrophoretic-based cytosorter. in Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007., 4160383, pp. 556-560, 2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007, Bangkok, Thailand, 07-01-16. https://doi.org/10.1109/NEMS.2007.352080

Numerical simulation and optimal design on a new dielectrophoretic-based cytosorter. / Leu, Tzong-Shyng; Kuo, Yao Jen.

Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007. 2007. p. 556-560 4160383.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Leu T-S, Kuo YJ. Numerical simulation and optimal design on a new dielectrophoretic-based cytosorter. In Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007. 2007. p. 556-560. 4160383 https://doi.org/10.1109/NEMS.2007.352080