One-pot synthesis of ene-lactams via N-debenzylation of keto-containing N-2,4-dimethoxylbenzylamides

Wai Ming Kan, Ching Lung Cheng, Ching Yuh Chern

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

A general method of ene-lactam preparation is described. Ene-lactams can be prepared efficiently from keto-containing N-2,4-dimethoxylbenzylamides in good to excellent yields. This method is applicable for the preparation of substituted δ-, γ-, and ε-ene-lactams and bicyclic ene-lactams.

Original languageEnglish
Pages (from-to)4257-4264
Number of pages8
JournalSynthetic Communications
Volume34
Issue number23
DOIs
Publication statusPublished - 2004

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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