One-pot synthesis of ene-lactams via N-debenzylation of keto-containing N-2,4-dimethoxylbenzylamides

Wai Ming Kan; Ching Lung Cheng; Ching Yuh Chern

doi:10.1081/SCC-200039335

One-pot synthesis of ene-lactams via N-debenzylation of keto-containing N-2,4-dimethoxylbenzylamides

Wai Ming Kan, Ching Lung Cheng, Ching Yuh Chern

Department of Pharmacology

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

A general method of ene-lactam preparation is described. Ene-lactams can be prepared efficiently from keto-containing N-2,4-dimethoxylbenzylamides in good to excellent yields. This method is applicable for the preparation of substituted δ-, γ-, and ε-ene-lactams and bicyclic ene-lactams.

Original language	English
Pages (from-to)	4257-4264
Number of pages	8
Journal	Synthetic Communications
Volume	34
Issue number	23
DOIs	https://doi.org/10.1081/SCC-200039335
Publication status	Published - 2004

All Science Journal Classification (ASJC) codes

Organic Chemistry

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10.1081/SCC-200039335

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title = "One-pot synthesis of ene-lactams via N-debenzylation of keto-containing N-2,4-dimethoxylbenzylamides",

abstract = "A general method of ene-lactam preparation is described. Ene-lactams can be prepared efficiently from keto-containing N-2,4-dimethoxylbenzylamides in good to excellent yields. This method is applicable for the preparation of substituted δ-, γ-, and ε-ene-lactams and bicyclic ene-lactams.",

author = "Kan, {Wai Ming} and Cheng, {Ching Lung} and Chern, {Ching Yuh}",

note = "Funding Information: This work was supported by the National Science Council, Taiwan, R.O.C. grants NSC92-2113-M415-004.",

year = "2004",

doi = "10.1081/SCC-200039335",

language = "English",

volume = "34",

pages = "4257--4264",

journal = "Synthetic Communications",

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publisher = "Taylor and Francis Ltd.",

number = "23",

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T1 - One-pot synthesis of ene-lactams via N-debenzylation of keto-containing N-2,4-dimethoxylbenzylamides

AU - Kan, Wai Ming

AU - Cheng, Ching Lung

AU - Chern, Ching Yuh

N1 - Funding Information: This work was supported by the National Science Council, Taiwan, R.O.C. grants NSC92-2113-M415-004.

PY - 2004

Y1 - 2004

N2 - A general method of ene-lactam preparation is described. Ene-lactams can be prepared efficiently from keto-containing N-2,4-dimethoxylbenzylamides in good to excellent yields. This method is applicable for the preparation of substituted δ-, γ-, and ε-ene-lactams and bicyclic ene-lactams.

AB - A general method of ene-lactam preparation is described. Ene-lactams can be prepared efficiently from keto-containing N-2,4-dimethoxylbenzylamides in good to excellent yields. This method is applicable for the preparation of substituted δ-, γ-, and ε-ene-lactams and bicyclic ene-lactams.

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U2 - 10.1081/SCC-200039335

DO - 10.1081/SCC-200039335

M3 - Article

AN - SCOPUS:10644266761

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JO - Synthetic Communications

JF - Synthetic Communications

SN - 0039-7911

IS - 23

ER -

One-pot synthesis of ene-lactams via N-debenzylation of keto-containing N-2,4-dimethoxylbenzylamides

Abstract

All Science Journal Classification (ASJC) codes

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