One-year follow-up of relapse to risky behaviors and incidence of syphilis among patients enrolled in the HIV case management program

Nai-Ying Ko, Hsiao Ying Liu, Hsin Chun Lee, Yi Yin Lai, Chia-Ming Chang, Nan-Yao Lee, Po-Lin Chen, Chi Jung Wu, Wen-Chien Ko

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A longitudinal prospective study was conducted at an AIDS designated hospital in Taiwan. The study aimed to determine the incidence of syphilis and to identify risk factors predicting new onset syphilis and relapse into risky behaviors among 117 patients enrolled in the HIV case management program for 1 year. Having a new episode of syphilis was defined as patients had a fourfold increase of serum rapid plasma reagin titers from baseline to 12-month follow-up. After enrollment, 17% relapsed in unprotected sexual intercourse. New onset syphilis was noted in ten (10.4%) participants, and all were men having sex with men. The incidence of syphilis was 5.8 per 100 person-years. Predictors of a new episode of syphilis were higher CD4 cell counts [hazard ratio (HR), 1.003; 95% confidence interval (CI), 1.00-1.006], and recreational drug use (HR, 18.89; 95% CI, 2.78-128.15). Regular screening for syphilis among patients retaining in HIV care remains necessary.

Original languageEnglish
Pages (from-to)1067-1074
Number of pages8
JournalAIDS and Behavior
Volume15
Issue number5
DOIs
Publication statusPublished - 2011 Jul 1

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Case Management
Syphilis
HIV
Recurrence
Incidence
Reagins
Confidence Intervals
Coitus
Street Drugs
CD4 Lymphocyte Count
Taiwan
Longitudinal Studies
Acquired Immunodeficiency Syndrome
Prospective Studies
Serum

All Science Journal Classification (ASJC) codes

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

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abstract = "A longitudinal prospective study was conducted at an AIDS designated hospital in Taiwan. The study aimed to determine the incidence of syphilis and to identify risk factors predicting new onset syphilis and relapse into risky behaviors among 117 patients enrolled in the HIV case management program for 1 year. Having a new episode of syphilis was defined as patients had a fourfold increase of serum rapid plasma reagin titers from baseline to 12-month follow-up. After enrollment, 17{\%} relapsed in unprotected sexual intercourse. New onset syphilis was noted in ten (10.4{\%}) participants, and all were men having sex with men. The incidence of syphilis was 5.8 per 100 person-years. Predictors of a new episode of syphilis were higher CD4 cell counts [hazard ratio (HR), 1.003; 95{\%} confidence interval (CI), 1.00-1.006], and recreational drug use (HR, 18.89; 95{\%} CI, 2.78-128.15). Regular screening for syphilis among patients retaining in HIV care remains necessary.",
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One-year follow-up of relapse to risky behaviors and incidence of syphilis among patients enrolled in the HIV case management program. / Ko, Nai-Ying; Liu, Hsiao Ying; Lee, Hsin Chun; Lai, Yi Yin; Chang, Chia-Ming; Lee, Nan-Yao; Chen, Po-Lin; Wu, Chi Jung; Ko, Wen-Chien.

In: AIDS and Behavior, Vol. 15, No. 5, 01.07.2011, p. 1067-1074.

Research output: Contribution to journalArticle

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AU - Chang, Chia-Ming

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